Dr. Jonathan Cachat joins Kratom Science Podcast host Brian Gallagher to talk about kratom research. Each episode we pick a study about kratom published in a peer-reviewed journal.
For a special 40th episode, Dr. Jon revisits research he led out of Tulane University in 2010 on psychoactive substance effects in zebrafish. Out of 40+ published papers from this research, we look at one focusing on zebrafish symptoms when in withdrawal from ethanol, diazepam, morphine and caffeine. We also talk about living in New …
Journal Club #40: Dr. Jon’s 2010 Zebrafish Research Read More »
Dr. Jon Cachat and Brian look at a survey conducted from 2019-2020. The survey found the majority of the 2,296 respondents with psychiatric conditions reported improvement in their condition following the consumption of kratom. Recently published by the American Psychological Association, the survey was authored by five past Kratom Science Podcast guests: Drs. Oliver Grundmann, …
Journal Club #39: Survey of Kratom Consumers with Psychiatric Conditions Read More »
Thailand has recently decriminalized kratom after 79 years of prohibition. In today’s episode of Kratom Science Journal Club, Dr. Cachat and Brian look at a study funded in part by the Thai government that analyzed kratom trees growing in various regions of Thailand. The team measured mitragynine levels, accounting for variables in climate such as …
Journal Club #38: Mitragynine in Kratom Trees in Thailand Read More »
Dr. Jon starts off talking about the art show that took place in October 2022 at the new Cannabis Museum in Athens Ohio. Then we cover a study out of Thailand on kratom’s effects on alpha-glucosidase and lipase, enzymes that are inhibited by medications for the treatment of diabetes. We see how kratom and mitragynine …
Journal Club #37: Kratom and Diabetes Study from Thailand Read More »
Dr. Jon and Brian look at a study (Farkas et al., 2022 https://doi.org/10.1016/j.ibneur.2022.08.007) in mice out of Temple University exploring whether mitragynine can help attenuate chemotherapy-induced peripheral neuropathic (CIPN). The team used oxaliplatin, a chemotherapy drug, to induce this condition in an equal number of male and female mice. Mitragynine was also combined with four …
Journal Club #36: Mitragynine for Chemotherapy-Induced Pain Read More »
Dr. Jon and Brian explore a study out of Thailand where goats meat goats ate feed supplemented with dried kratom leaves. What effect did this have on the goats body weight, cholesterol, blood, and feed conversion ratio? Even if it does work, will farmers be able to afford kratom as a feed supplement, given the …
Dr. Jon and Brian take a break from kratom to look at the recently released Netflix documentary series hosted by Michael Pollan, How to Change Your Mind. In related good news: the DEA backed off its decision to schedule five psychedelics. Hamilton Morris tweets. “Today the DEA withdrew their plan to prohibit DiPT, 4-HO-DiPT, 5-MeO-MiPT, …
Journal Club #34: How to Change Your Mind Documentary Read More »
Dr. Cachat and Brian look at a letter (Smith et al, 2022) authored by former Kratom Science Podcast guests Dr. Kirsten Smith, Dr. Oliver Grundmann, Dr. Chris McCurdy, Dr. Darshan Singh, and other experts in the kratom field. The letter questions a systematic review (Broyan et al, 2022) of kratom case reports that offers buprenorphine …
Journal Club #33: Kratom Scientists Pen Letter Questioning Case Report Review Read More »
Today on Journal Club, Dr. Jon Cachat look at a study in 2021 out of University of Colorado, Boulder in cooperation with Leafly that examines nearly 90,000 cannabis samples. Does Indica, Sativa, and Hybrid really mean anything in terms of psychoactive effects? Are cannabis strains labelled consistently in terms of cannabinoid and terpene content? We …
Journal Club #32: Cannabis Strains, Cannabinoids, and Terpenes Read More »
Perhaps the most important paper Dr. Jon and Brian have covered so far, “Understanding Kratom: A Guide for Healthcare Providers” is a comprehensive introduction to kratom for those who provide direct care to kratom consumers, such as physicians or mental health specialists. In this paper spearheaded by past Kratom Science Podcast guest, Dr. Marc Swogger, …
Journal Club #31: A Kratom Guide for Healthcare Providers Read More »
