Research

Pennsylvania House Democrats Compare Kratom to Heroin in Pseudoscientific Tweet

On May 2nd, the Pennsylvania House Democratic Policy Committee @PADemPolicy posted on Twitter that it was “in Allentown with @RepSchlossberg for a roundtable on the Evolving Epidemic: Opioids and Treatment Options.” Then in a reply to this tweet, wrote “Kratom is widely available but suppresses breathing much the same way as heroin.” As anyone who …

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Study: Mitragynine does not rely on its metabolism into 7-hydroxymitragynine to produce pain relieving effects

In a new study by the team at University of Florida, scientists found that the metabolite 7-hydroxymitragynine does not account for the pain-relieving effects of its parent alkaloid, mitragynine (Berthold et al., 2021). Here we investigated the hotplate antinociception, pharmacokinetics, and tissue distribution of mitragynine and 7-hydroxymitragynine at equianalgesic oral doses in…mice to determine the …

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Interview with Dr. Fabian Pitter Steinmetz on Toxicology and Advocacy by Scientists for Better Drug Policy

Dr. Fabian Pitter Steinmetz is a toxicologist from Germany who in 2021 testified for the World Health Organization’s (WHO) 44th Expert Committee on Drug Dependence (ECDD). There, Dr. Steinmetz gave the case for why kratom should be kept legal. As a member for the European Coalition for Just and Effective Drug Policies (ENCOD), he is …

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Caffeine is an Addictive, Deadly Drug

Coffee is a tropical evergreen plant originating in Ethiopia but now grown worldwide. Two species, Coffea arabica and Coffea canephora, are predominantly sold as a recreational stimulant. Referred to “joe”, “java”, “brew”, “mud”, “liquid cocaine”, “espresso” and “go juice”, coffee is a drug of abuse, primarily used for its psychoactive and stimulant effects, similar to …

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Interview with Dr. Lance McMahon, Chair of Dept of Pharmacodynamics, UF College of Pharmacy

Dr. Lance McMahon is Chair of the Department of Pharmacodynamics at University of Florida College of Pharmacy. Dr. McMahon is involved in pioneering kratom research that looks at the various kratom alkaloids, how they function on our brain receptors, and how that creates kratom’s complex effects on our bio. We talk about this research, where …

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Combining traditional plant medicine with modern medical technology

A pharmacologist today may regard traditional and plant medicine as primitive, and may entirely disregard thousands of years of use and thousands of modern-day testimonies of positive outcomes because it has not been through the rigors of hard science. On the other hand, the massive spread of anti-science misinformation has cast sometimes unreasonable doubt on …

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A list of baseless claims that kratom causes hallucinations

In October 2018 we covered a sensationalist news story out of Florida where the director of a for-profit rehabilitation center claimed that kratom caused hallucinations (Scripps Media, 2018). Multiple news stories, press releases by government agencies, and even peer-reviewed published studies have made this claim, all without a shred of hard evidence. The most comprehensive …

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Cleveland Clinic uses O-desmethyltramadol overdoses to support its claim that “kratom has even caused death”

Cleveland Clinic is one of the highest ranking and most reputable hospital systems in the United States. The nonprofit established in 1921 (Happy Anniversary!) serves over 7 million patients per year, houses the top cardiology program in the nation, and has international campuses in Canada, the UK, and the United Arab Emirates. The Cleveland Clinic …

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Does the FDA want to control kratom because they know it’s safe?

The Food and Drug Administration (FDA) has been an outspoken enemy of legal kratom since 2012. The FDA’s official stance on kratom as of 2019 has been to warn Americans that kratom is a dangerous drug that should never be consumed. The U.S. Food and Drug Administration is warning consumers not to use Mitragyna speciosa, …

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