Research

Does the FDA want to control kratom because they know it’s safe?

The Food and Drug Administration (FDA) has been an outspoken enemy of legal kratom since 2012. The FDA’s official stance on kratom as of 2019 has been to warn Americans that kratom is a dangerous drug that should never be consumed. The U.S. Food and Drug Administration is warning consumers not to use Mitragyna speciosa, …

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What’s causing hair loss, a rare side effect in kratom consumers?

So far, no scientific evidence has been found linking kratom and hair loss, but it seems from several online forums that a very small percentage of American consumers are experiencing this bizarre side effect. Many also report that after discontinuing kratom, their hair grows back. What could be the cause? I could find virtually no …

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Interview with Dr. Oliver Grundmann, Professor of Medicinal Chemistry and Kratom Researcher, University of Florida

An audio version of this interview can be found on the Kratom Science Podcast #40 Kratom Science: How did you become involved with studying kratom? Oliver Grundmann: It’s an interesting way, how I got involved with kratom. In 2015 one of my Masters students who works in the forensic field with a forensic toxicology lab …

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Correlation Found Between Thai Kratom Users and “Good” Cholesterol Levels

A new study from Thailand (La-up, 2021) found traditional users of kratom had elevated levels of high-density lipoprotein (HDL or “good” cholesterol) and low levels of triglycerides, or “fats from the food we eat that are carried in the blood” (Cleveland Clinic 2019). High HDL, low levels of low-density lipoprotein (LDL or “bad” cholesterol), and …

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Kratom Under a Microscope

A group of scientists from the Malaysian Agricultural Research and Development Institute have documented the anatomy of the kratom plant. In the study published Tropical Life Sciences Research, scientists documented not only the anatomy, but the “micromorphology characteristics” of kratom plants collected from Malaysia. The study provided botanical evidence kratom is indeed a species of …

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List of “New” Psychoactive Substances of Natural Origin

Note: This article is a summary of the journal article cited as follows:Gonçalves, J., Luís, Â., Gallardo, E., & Duarte, A. P. (2021). Psychoactive Substances of Natural Origin: Toxicological Aspects, Therapeutic Properties and Analysis in Biological Samples. Molecules (Basel, Switzerland), 26(5), 1397. https://doi.org/10.3390/molecules26051397Full text: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961374/ Scientists from Portugal, where the possession and consumption of all …

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Teenager Attempts Suicide by Swallowing 45 Kratom Capsules

In a 2020 case report, a teenage girl intentionally overdosed on 45 kratom capsules (500mg each = 22.5 grams or 4/5 ounce). After suffering from severe depression, the 15 year old obtained the capsules from her father, and swallowed them in an attempted suicide. On exam, patient complained of dry mouth, dizziness, restlessness, palpitations, nausea, …

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Inteview with Pharmacokineticist and Kratom Researcher Dr. Abhisheak Sharma

For audio of this interview as well as studies cited here see Kratom Science Podcast #45 KratomScience: You have your background in pharmacokinetics. What made you interested in going into that field? Dr. Abhisheak Sharma: So basically I did my PhD in 2015 and I moved to the States to do my post-doctoral studies with …

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