General

Interview with Dr. Fabian Pitter Steinmetz on Toxicology and Advocacy by Scientists for Better Drug Policy

Dr. Fabian Pitter Steinmetz is a toxicologist from Germany who in 2021 testified for the World Health Organization’s (WHO) 44th Expert Committee on Drug Dependence (ECDD). There, Dr. Steinmetz gave the case for why kratom should be kept legal. As a member for the European Coalition for Just and Effective Drug Policies (ENCOD), he is …

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Caffeine is an Addictive, Deadly Drug

Coffee is a tropical evergreen plant originating in Ethiopia but now grown worldwide. Two species, Coffea arabica and Coffea canephora, are predominantly sold as a recreational stimulant. Referred to “joe”, “java”, “brew”, “mud”, “liquid cocaine”, “espresso” and “go juice”, coffee is a drug of abuse, primarily used for its psychoactive and stimulant effects, similar to …

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Scientists: Mitragynine makes mice dumber. Also scientists: Mitragynine makes rats smarter

Last week we told you about a study published in September 2021 that showed cognitive impairment in high-dose mitragynine (MG), the main alkaloid in kratom. The study was also the subject of Kratom Science Journal Club #26. Researchers discovered that very high doses of MG, like THC and morphine, attach to CB1 receptors and cause …

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Interview with Dr. Lance McMahon, Chair of Dept of Pharmacodynamics, UF College of Pharmacy

Dr. Lance McMahon is Chair of the Department of Pharmacodynamics at University of Florida College of Pharmacy. Dr. McMahon is involved in pioneering kratom research that looks at the various kratom alkaloids, how they function on our brain receptors, and how that creates kratom’s complex effects on our bio. We talk about this research, where …

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Study: High-Dose Mitragynine Interacts with Cannabinoid Receptor to Impair Cognitive Functioning

A comprehensive and detailed study in mice from University of Science, Malaysia revealed mitragynine in very high doses is an agonist (binds to and activates) cannabinoid receptor Type 1 (CB1). Mice administered with high-dose mitragynine demonstrated similar reward-seeking behavior and cognitive impairment as mice administered with morphine and THC. Mice that received high-dose mitragynine, morphine, …

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Kratom Companies Involved in Civil Forfeiture

Pittsburgh, PA A civil forfeiture action filed in Pittsburgh’s U.S. District Court spells bad news for several kratom companies across the country.  The companies in question: Coastline Kratom, Kratom Crazy, and Best Kratom, are all ceasing operations, effective immediately. Two of the companies, Coastline Kratom and Kratom Crazy, are sister companies, previously owned by a …

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Transcript of Kratom Science Podcast #57: Representatives of PPHI, Indonesian Farmers’ Co-op

Note: This content is the result of (1) Brian Gallagher’s interview with Mr. Suhairi Ery, Daily Chairman of PPHI and kratom farmer Mr. Jamaluddin Junaid and translated by Mr. Ashari, (2) Correspondence between Mr. Fadli Ashari and Brian Gallagher via email. (3) Mr. Ashairi wrote the “about” section. ….Questions were written by both Brian Gallagher …

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