Kratom and Alcoholism

Scientists have found evidence that kratom can help alleviate opioid withdrawal and cut down on cravings for recovering opiate addicts. Emerging research and experiential testimony indicates that kratom also cuts…

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Kratom as a Harm Reduction Tool

The term harm reduction refers to a public health strategy to reduce negative consequences resulting from activities such as illicit substance use and addiction. Whereas abstinence from dangerous drugs may…

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Do you take kratom for ADHD ?
Photo by Robina Weermeijer https://unsplash.com/photos/so1L3jsdD3Y

Do you take kratom for ADHD ?

Do you have attention deficit hyperactivity disorder (ADHD) and consume kratom? Or have you tried kratom for ADHD symptoms or side effects of medications? How did it make you feel?…

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Is Kratom a Drug?
1950s ad for methedrine, aka legal methamphetamine

Is Kratom a Drug?

Is kratom a drug, a medicinal herb, a dietary supplement, a "safe food", a tea? These terms have a whole lot to do with social perception, a little to do…

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Toxic Levels of Kratom and LD50 of Mitragynine
By User:Ring0 - Own work, Public Domain, https://commons.wikimedia.org/w/index.php?curid=831924

Toxic Levels of Kratom and LD50 of Mitragynine

Mitragynine is the most abundant alkaloid in kratom. Kratom contains about 40 alkaloids that we know of. All of the alkaloids combined make up only 0.5-1.5% of the total leaf…

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“Kratom addiction” used as defense in trial of Customs Officer who stole thousands from travelers

Joseph Cialone, a US Customers officer, is being charged with a felony for stealing approximately $10,000 from travelers coming into the United States in violation of 18 U.S. Code § 654.…

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Study shows mitragynine metabolizes into 7-Hydroxymitragynine
Illustration from Kruegel study of MG being metabolized into 7OH before acting on the MOR to produce pain relieving effects

Study shows mitragynine metabolizes into 7-Hydroxymitragynine

Citation Kruegel AC, Uprety R, Grinnell SG, et al. 7-Hydroxymitragynine Is an Active Metabolite of Mitragynine and a Key Mediator of Its Analgesic Effects. ACS Cent Sci. 2019;5(6):992-1001. doi:10.1021/acscentsci.9b00141 Summary…

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