pain – Kratom Science

Journal Club #36: Mitragynine for Chemotherapy-Induced Pain

Journal Club with Dr. Jonathan Cachat

Journal Club #36: Mitragynine for Chemotherapy-Induced Pain

00:00 / 43:43

Dr. Jon and Brian look at a study (Farkas et al., 2022 https://doi.org/10.1016/j.ibneur.2022.08.007) in mice out of Temple University exploring whether mitragynine can help attenuate chemotherapy-induced peripheral neuropathic (CIPN). The team used oxaliplatin, a chemotherapy drug, to induce this condition in an equal number of male and female mice. Mitragynine was also combined with four …

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255 Pages of First-Hand Kratom Consumer Experiences

3 Comments / General, Kratom Stories / By Brian

Thousands of comments posted to various pages of KratomScience.com from 2014 – 2021 reflected first-hand experiences with the consumption of kratom. Commenters independently found KratomScience.com and shared their experiences without solicitation. Though users can comment anonymously under different usernames and IP addresses, efforts were made to group together multiple comments made under the same email …

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Journal Club #28: Mitragynine Does Not Rely on 7-hydroxymitragynine for Pain Relief Effects

Journal Club with Dr. Jonathan Cachat

Journal Club #28: Mitragynine Does Not Rely on 7-hydroxymitragynine for Pain Relief Effects

00:00 / 39:20

Dr. Cachat and host Brian Gallagher look at a groundbreaking study from University of Florida School of Pharmacy showing mitragynine has pain relieving effects independent of its metabolism into 7-hydroxymitragynine. This could be revolutionary in the study of kratom as a safer pain medicine. We go on to talk about the cannabis testing lab that …

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64. Veterans Day Special: A Look Back on Four Veterans Who Told Us Their Kratom Stories

Kratom Science Podcast

64. Veterans Day Special: A Look Back on Four Veterans Who Told Us Their Kratom Stories

00:00 / 54:34

November 11, 2021 is Veterans Day! We take a look back at four veterans of the United States military who had a kratom story to share. From episode #13, Drew Turner is a US Navy veteran who served in Iraq and Guantanamo Bay. He appeared in the kratom documentary A Leaf of Faith. Drew discusses …

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56. Injuries, Pain, Cancer, Heart Attack, Endometriosis, Suicide Attempt: A Survival Story w/ Amanda Marie

Kratom Science Podcast

56. Injuries, Pain, Cancer, Heart Attack, Endometriosis, Suicide Attempt: A Survival Story w/ Amanda Marie

00:00 / 44:24

Amanda Marie is a farmer and construction worker living in New Mexico. She had been severely injured due to a skating accident when she was 13, and later a car accident for which she developed lifelong chronic pain. She went on to develop Fibromyalgia, Multiple Sclerosis, and had a heart attack before she was diagnosed …

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52. The Other Crime of the Century: State-Sanctioned Torture of Pain Patients w/ Dr. Thomas Kline

Kratom Science Podcast

52. The Other Crime of the Century: State-Sanctioned Torture of Pain Patients w/ Dr. Thomas Kline

00:00 / 1:11:58

You may have seen HBO’s documentary The Crime of the Century about pharmaceutical companies influencing doctors to prescribe an abundance of pain medication. But there’s another story that may make for a sequel. CDC guidelines combined with DEA threats to doctors are now leaving chronic pain patients without the access to opioid pain medication that …

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49. Comedian Shane Mauss Talks Science Podcasting and Kratom

Kratom Science Podcast

49. Comedian Shane Mauss Talks Science Podcasting and Kratom

00:00 / 1:12:02

Shane Mauss is a stand up comedian who has appeared on Late Night with Conan O’Brien, Jimmy Kimmel Live, The Joe Rogan Experience, WTF with Marc Maron, Comedy Central, The Green Room with Paul Provenza, and Getting Doug with High, just to name a few. For the past 7 years he’s interviewed scientists on a …

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46. Surviving Decades-Long Severe Chronic Pain with Dijon Evans

Kratom Science Podcast

46. Surviving Decades-Long Severe Chronic Pain with Dijon Evans

00:00 / 52:43

Dijon Evans is a survivor of severe chronic pain, and as past Kratom Science Podcast guest Nina Ajdin refers to her, a warrior. At 16 and working as a lifeguard, Dijon injured her leg trying to save a little boy from drowning. Doctors applied a cast too tight, and despite days of pleading, they would …

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Journal Club #14, Q&A Part 1: Kratom and Liver Enzymes, Alcohol, Pain Management, and Serotonin

Journal Club with Dr. Jonathan Cachat

Journal Club #14, Q&A Part 1: Kratom and Liver Enzymes, Alcohol, Pain Management, and Serotonin

00:00 / 34:05

Note: Nothing in this podcast or on KratomScience.com is intended to be medical advice, nor should it be taken as such. We’re not medical doctors. Please don’t listen to podcasts for advice on what you should or should not put in your body. For episode #14, Dr. Jonathan Cachat answers half of the remaining question …

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39. Recovery in the UK with Paul W.

Kratom Science Podcast

39. Recovery in the UK with Paul W.

00:00 / 38:41

Paul W was prescribed hydrocodone following a car accident… the beginning of a long journey with opioid pain pills. Living in Florida during the golden age of pill mills (early 2000s) didn’t help. After addiction, recovery, and relapse Paul moved to Italy where he met his future husband. They moved to England where Paul relapsed …

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