Drug Prohibition is the refusal by a government to reasonably regulate psychoactive substance markets, facilitate open research of psychoactive substances, and provide effective healthcare to people who use drugs. One purpose of drug prohibition is to expand the powers of law enforcement to legally oppress certain communities. John Ehrlichmann, a policy advisor to President Richard …
Spoiler alert: kinda, but its more the quercetin in kratom, which is available in many food plants and as a dietary supplement on its own. This study comes to us from a team at Universitas Nahdlatul Ulama Surabaya (UNUSA) in Surabaya, Indonesia, on the island of Java, south of the island of Kalimantan, where most …
Journal Club #27: Does Kratom Kill…E-coli and Streptococcus Pneumoniae? Read More »
Dr. Fabian Pitter Steinmetz is a toxicologist from Germany who in 2021 testified for the World Health Organization’s (WHO) 44th Expert Committee on Drug Dependence (ECDD). There, Dr. Steinmetz gave the case for why kratom should be kept legal. As a member for the European Coalition for Just and Effective Drug Policies (ENCOD), he is …
November 11, 2021 is Veterans Day! We take a look back at four veterans of the United States military who had a kratom story to share. From episode #13, Drew Turner is a US Navy veteran who served in Iraq and Guantanamo Bay. He appeared in the kratom documentary A Leaf of Faith. Drew discusses …
64. Veterans Day Special: A Look Back on Four Veterans Who Told Us Their Kratom Stories Read More »
Soren Shade visits Brian in Pittsburgh bearing gifts: mature kratom leaves and a kratom plant the Top Tree Herbs greenhouse in West Virginia. This is the 2nd time the Hamilton’s Pharmacopeia producer and kratom entrepreneur has been on the podcast – the first time being #47. Brian chews kratom for the first time, and we …
Dr. Lance McMahon is Chair of the Department of Pharmacodynamics at University of Florida College of Pharmacy. Dr. McMahon is involved in pioneering kratom research that looks at the various kratom alkaloids, how they function on our brain receptors, and how that creates kratom’s complex effects on our bio. We talk about this research, where …
Dr. JC and Brian look at a study out of University of Science, Malaysia. The comprehensive and detailed study in mice from University of Science, Malaysia revealed mitragynine in very high doses is an agonist (binds to and activates) cannabinoid receptor Type 1 (CB1). Mice administered with high-dose mitragynine demonstrated similar reward-seeking behavior and cognitive …
Journal Club #26: High Dose Mitragynine Causes Cognitive Impairment in Mice Read More »
A comprehensive and detailed study in mice from University of Science, Malaysia revealed mitragynine in very high doses is an agonist (binds to and activates) cannabinoid receptor Type 1 (CB1). Mice administered with high-dose mitragynine demonstrated similar reward-seeking behavior and cognitive impairment as mice administered with morphine and THC. Mice that received high-dose mitragynine, morphine, …
Dr. Fabian Pitter Steinmetz is a senior toxicologist from Germany and an outspoken advocate for harm reduction and science-based, rational drug policy. On October 11, 2021, representing the European Coalition for Just and Effective Drug Policies, Dr. Steinmetz testified against kratom prohibition for the World Health Organization’s 44th Expert Committee on Drug Dependence . Dr. …
62. Dr. Fabian Pitter Steinmetz, Toxicologist Who Testified at the WHO Hearing on Kratom Read More »
Dr. Jon Cachat and host Brian Gallagher look at a study that examined dopamine levels with an electrochemical sensor in rats administered with various levels of mitragynine. Dopamine release was detected as significant levels after a high dose of mitragynine after 4 days. Questions explored in this episode include: Does this accurately measure the kratom …
Journal Club #25: Dopamine Response to Mitragynine in Rats Read More »
