Brian and Kailee talk about the results of the state marijuana and psychedelics referendums from Tuesday’s election, a wrongful death lawsuit against kratom companies and the American Kratom Association in Georgia, a death in Transylvania County, North Carolina attributed to suboxone mixed with vaped kratom, a drug company is undergoing human clinical trials for a …
The parents of a man who died after ingesting kratom extract are suing multiple kratom companies and the American Kratom Association (AKA). In a 45 page complaint, Dana and John Pope allege their 23 year old son, Ethan, died after purchasing and ingesting “one or more bottles” of OPMS extract from two stores in two …
Dr. Jon starts off talking about the art show that took place in October 2022 at the new Cannabis Museum in Athens Ohio. Then we cover a study out of Thailand on kratom’s effects on alpha-glucosidase and lipase, enzymes that are inhibited by medications for the treatment of diabetes. We see how kratom and mitragynine …
Journal Club #37: Kratom and Diabetes Study from Thailand Read More »
Drew Turner is a U.S. Navy combat veteran who appeared in the documentary A Leaf of Faith. We talk about an experimental extract he tried, recreational cannabis in his home of Michigan, Biden’s federal cannabis possession pardons, the present and future of kratom and cannabis regulation could look like, rare cases of severe kratom toxicity …
Another Louisiana parish turned back the clock on rational drug policy and decided to criminalize kratom consumers. On October 10, the Rapides Parish Police Jury (the governing body of the parish, made up of elected officials, much like a county council) voted unanimously to fine and imprison citizens for the possession and sale of kratom. …
Rapides Parish, Louisiana Criminalizes Kratom Consumers Read More »
Kailee joins Brian to cover kratom and cannabis news for the past month. This month: Biden pardons thousands convicted of simple possession of weed, Michigan has a bill regulating kratom, a Welsh man can’t believe kratom importation is illegal in the UK, lab testing will be required for kratom exports from Thailand, and Kratom Science …
Joanna Bernstein is a writer originally from Pittsburgh who now resides in Oregon. In 2014 Joanna had a painful bacterial infection that started her on opiates. She eventually developed an addiction and wrote about her experience with recovery in a “3/4 house” in Pittsburgh’s Carrick neighborhood. Later she would nearly relapse after being denied pain …
89. Journalist Joanna Bernstein on Kratom as Harm Reduction and M.A.T. Read More »
The conversation around kratom is as complex as the plant itself. For kratom to manifest in our society as a healing plant instead of a perceived dangerous drug, the science of kratom needs to become conventional wisdom. For the millions of Americans kratom has already helped, we can’t afford to spend 80 years digging our …
Why engaging with kratom misinformation hurts more than helps Read More »
Dr. Jon and Brian look at a study (Farkas et al., 2022 https://doi.org/10.1016/j.ibneur.2022.08.007) in mice out of Temple University exploring whether mitragynine can help attenuate chemotherapy-induced peripheral neuropathic (CIPN). The team used oxaliplatin, a chemotherapy drug, to induce this condition in an equal number of male and female mice. Mitragynine was also combined with four …
Journal Club #36: Mitragynine for Chemotherapy-Induced Pain Read More »
A Vancouver drug company announced that it has filed a patent for a deuterated form of 7-hydroxymitragynine (7-HMG) called D7-h. The company, Nirvana Life Sciences Inc., intends to pursue D7-h as a pain relieving drug, citing 7-HMG’s partial opioid agonism, and the deuteration process that they say makes the drug last longer. A deuterated drug …
Is it a good idea to make a 7-hydroxymitragynine based drug? Read More »
