kratom

Journal Club #28: Mitragynine Does Not Rely on 7-hydroxymitragynine for Pain Relief Effects

Journal Club with Dr. Jonathan Cachat
Journal Club with Dr. Jonathan Cachat
Journal Club #28: Mitragynine Does Not Rely on 7-hydroxymitragynine for Pain Relief Effects
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Dr. Cachat and host Brian Gallagher look at a groundbreaking study from University of Florida School of Pharmacy showing mitragynine has pain relieving effects independent of its metabolism into 7-hydroxymitragynine. This could be revolutionary in the study of kratom as a safer pain medicine. We go on to talk about the cannabis testing lab that …

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71. Marcelle Morfin on Chronic Pain and Kratom Advocacy

Kratom Science Podcast
Kratom Science Podcast
71. Marcelle Morfin on Chronic Pain and Kratom Advocacy
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Marcelle Morfin got a back injury while serving in the Army in 2006, and that was the beginning of her chronic pain journey. She was later diagnosed with degenerative disk disease, osteoarthritis, fibromyalgia, IBS, and cervical stenosis with myelopathy. She had been prescribed opioid pain medication, but had an aversion to taking pills. In 2017, …

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Kratom Prohibition Bills Introduced in States of Washington, Kentucky

January 18, 2022 Bills have been introduced in Washington and Kentucky that would place kratom on the list of Schedule 1 substances in those states. In Kentucky, Representative Josh Calloway introduced HB142 into the state’s House of Representatives. If passed into law, kratom would be included on the list of controlled substances that are unlawful …

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70. Shawn Wenzel on Living with Degenerative Disk Disease

Kratom Science Podcast
Kratom Science Podcast
70. Shawn Wenzel on Living with Degenerative Disk Disease
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My guest from Denver Colorado was diagnosed with degenerative disk disease and lives with severe chronic pain. Unable to receive adequate pain management, she found kratom, uses it in moderate amounts, and it works for her. This Shawn Wenzel and this is her kratom story. Disclaimer: None of the content in this or any episode …

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69. Dr. Christopher McCurdy and Dr. Brian Pearson on the Future of Kratom

Kratom Science Podcast
Kratom Science Podcast
69. Dr. Christopher McCurdy and Dr. Brian Pearson on the Future of Kratom
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Dr. Chris McCurdy is a medicinal chemist who has done groundbreaking research on kratom since 2004, starting at the University of Mississippi. In 2017 Dr. McCurdy moved to the University of Florida College of Pharmacy where he continues his research today with an expert team of pharmacologists, unlocking the function of kratom’s many alkaloids and …

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Pearl River County, Mississippi Board Wants to Ban Kratom

Mississippi has a long history with kratom. Dr. Christopher McCurdy co-authored several groundbreaking kratom studies from 2008-2016 working out of The University of Mississippi. Due in part to a law enforcement task force touring around the state to lobby for prohibition, kratom is now illegal in several towns and counties, including Oxford, the home town …

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Study: Mitragynine does not rely on its metabolism into 7-hydroxymitragynine to produce pain relieving effects

In a new study by the team at University of Florida, scientists found that the metabolite 7-hydroxymitragynine does not account for the pain-relieving effects of its parent alkaloid, mitragynine (Berthold et al., 2021). Here we investigated the hotplate antinociception, pharmacokinetics, and tissue distribution of mitragynine and 7-hydroxymitragynine at equianalgesic oral doses in…mice to determine the …

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European Kratom Alliance Announces its Formation

Kratom advocates in Europe have announced the formation of the European Kratom Alliance (EKA). The group made this announcement last week on r/kratom: It’s been five months since we have started working on this project in secrecy. It started with the WHO debacle, but we have finally made it. As of yesterday, we have formally …

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68. Dirk Netter, Author of Kratom: Ethnobotany, Application, and Culture

Kratom Science Podcast
Kratom Science Podcast
68. Dirk Netter, Author of Kratom: Ethnobotany, Application, and Culture
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Dirk Netter from Germany is the author of one of the only German language books on kratom called Kratom: Ethnobotany, Application, and Culture. As a student at Phillips University in Marburg, Germany he formed the Student Association for Interdisciplinary Psychedelic Research. Dirk Netter has active in the formation of a European kratom alliance to advocate …

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