Archives: Podcast

Journal Club #6: 1972 Animal Study Shows the Promise of Mitragynine

Journal Club with Dr. Jonathan Cachat
Journal Club with Dr. Jonathan Cachat
Journal Club #6: 1972 Animal Study Shows the Promise of Mitragynine
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Citation: Macko E, Weisbach JA, Douglas B. Some observations on the pharmacology of mitragynine. Archives Internationales de Pharmacodynamie et de Therapie. 1972 ;198(1):145-161. We discuss this study from 1972 that tested the effects of mitragynine in rats, mice, cats, dogs, and monkeys. Dr. Jon talks about the difference between now and then in pharmacology labs. …

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37. Sober October Starts Early

Kratom Science Podcast
Kratom Science Podcast
37. Sober October Starts Early
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Just me this time around. I talk about a soon-to-be-released document I’ve been working on through COVID that’s 200 pages of kratom testimonials from over 800 consumers who posted to KratomScience.com. I talk about a study on kratom and metabolism I blogged about here https://www.kratomscience.com/2020/09/22/study-shows-mitragynine-metabolizes-into-7-hydroxomitragynine/. And I talk about my own history of drinking alcohol …

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Journal Club w/ Dr. Jonathan Cachat #5: Mitragynine Study in Rats Leads to Interesting Conclusions

Journal Club with Dr. Jonathan Cachat
Journal Club with Dr. Jonathan Cachat
Journal Club w/ Dr. Jonathan Cachat #5: Mitragynine Study in Rats Leads to Interesting Conclusions
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Dr. Cachat and I talk about a study that tested rats with morphine, mitragynine, naloxone, buprenorphine, and rimonabant, and measured responses based on food-reinforcement training. The study concluded “The findings suggest that MG does not induce physiological dependence but can alleviate the physical symptoms associated with morphine withdrawal”. We talk about how the rats are …

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36. Surviving Abuse and Addiction with Julie Current

Kratom Science Podcast
Kratom Science Podcast
36. Surviving Abuse and Addiction with Julie Current
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Julie Current is a survivor. She had a rough childhood and as an adult she survived physical abuse that led to multiple disabilities like PTSD, chronic pain, and epilepsy. With kratom, kava, and cannabis as tools, she’s coming up on two years sober on October 28. This is Julie Current and this is her kratom …

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35. Kratom in the Workplace with Michael McCunney

Kratom Science Podcast
Kratom Science Podcast
35. Kratom in the Workplace with Michael McCunney
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Working in a competitive environment in the sales and marketing field, my guest Michael McCunney uses kratom as a stimulant, cognitive boost, and for general well-being. We talk about the importance of doing research, finding a good source, discovering your dose, and staying hydrated. Music: Risey, “Memories of Thailand” The Kratom Science Podcast is produced …

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Journal Club w/ Dr. Jonathan Cachat #4: Human Evolution and Psychoactive Plants, Scratching the Surface of Kratom History, and Kratom Alkaloids

Journal Club with Dr. Jonathan Cachat
Journal Club with Dr. Jonathan Cachat
Journal Club w/ Dr. Jonathan Cachat #4: Human Evolution and Psychoactive Plants, Scratching the Surface of Kratom History, and Kratom Alkaloids
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This episode, Dr. Jon and I use the journal article “Following the Roots of Kratom” published in 2015 by BioMed Research International as a jumping off point to talk about kratom history, human evolution and psychoactive plants, Terence McKenna’s “Stoned Ape” theory, and drug in religious cults . Plus, we answer listener mail about kratom …

Journal Club w/ Dr. Jonathan Cachat #4: Human Evolution and Psychoactive Plants, Scratching the Surface of Kratom History, and Kratom Alkaloids Read More »

34. Rod The Steelworker Switches to Kratom From Norco for Chronic Pain

Kratom Science
Kratom Science
34. Rod The Steelworker Switches to Kratom From Norco for Chronic Pain
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Rod the Steelerworker is from Michigan and has been a steelworker for 24 years. As a young man his hobbies were skateboarding and 4-wheeling. As a result of those hobbies, a career doing repetitive physical labor, along with Degenerative Disk Disease, diverticulitis, and IBS, he suffers from chronic pain. A prescription to Norco led him …

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Journal Club with Dr Jonathan Cachat #3: Kratom Addiction, Listener Mail, and Elephants on LSD

Journal Club with Dr. Jonathan Cachat
Journal Club with Dr. Jonathan Cachat
Journal Club with Dr Jonathan Cachat #3: Kratom Addiction, Listener Mail, and Elephants on LSD
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Dr. Jon Cachat and I talk about the article “Kratom instrumentalization for severe pain self-treatment resulting in addiction – A case report of acute and chronic subjective effects” – This is an open access article that you can read for free https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378692/ Müller, E., Hillemacher, T., & Müller, C. P. (2020). Kratom instrumentalization for severe …

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Journal Club with Dr. Jonathan Cachat #2: “The Potential for Kratom as an Antidepressant and Antipsychotic”

Journal Club with Dr. Jonathan Cachat
Journal Club with Dr. Jonathan Cachat
Journal Club with Dr. Jonathan Cachat #2: "The Potential for Kratom as an Antidepressant and Antipsychotic"
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This is the Kratom Science Journal Club with Dr. Jonathan Cachat, neuroscientist and expert in psychopharmacology. In each episode we discuss an article in a peer reviewed journal. For episode 2 we discuss the article, “The Potential for Kratom as an Antidepressant and Antipsychotic” published in Yale Journal of Biology and Medicine, edition 93, June …

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33. Pain Management for Interstitial Cystitis with Maranda Flynn

Kratom Science Podcast
Kratom Science Podcast
33. Pain Management for Interstitial Cystitis with Maranda Flynn
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Maranda was diagnosed at 22 with interstitial cystitis, a painful bladder disease. She went into pain management and became addicted to opiates. After 3 years a friend introduced her to kratom. she got out of opiate hell, and was able to be present for her children and husband, who also used kratom to beat alcoholism. …

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