Archives: Podcast

Journal Club #27: Does Kratom Kill…E-coli and Streptococcus Pneumoniae?

Journal Club with Dr. Jonathan Cachat
Journal Club with Dr. Jonathan Cachat
Journal Club #27: Does Kratom Kill...E-coli and Streptococcus Pneumoniae?
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Spoiler alert: kinda, but its more the quercetin in kratom, which is available in many food plants and as a dietary supplement on its own. This study comes to us from a team at Universitas Nahdlatul Ulama Surabaya (UNUSA) in Surabaya, Indonesia, on the island of Java, south of the island of Kalimantan, where most …

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65. Claudia Merandi, Pain Patient Advocate and Author

Kratom Science Podcast
Kratom Science Podcast
65. Claudia Merandi, Pain Patient Advocate and Author
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Hulu’s final episode of Dopesick aired yesterday. “I cancelled my Hulu account,” says my guest, Claudia Merandi. “I called it Dopesickening. Hollywood had to profit off the pain community… I refuse to watch.” Claudia Merandi has suffered from Chrohn’s disease since she was a child, as documented in her book Crohn’s: The Other ‘C’ Word: …

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64. Veterans Day Special: A Look Back on Four Veterans Who Told Us Their Kratom Stories

Kratom Science Podcast
Kratom Science Podcast
64. Veterans Day Special: A Look Back on Four Veterans Who Told Us Their Kratom Stories
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November 11, 2021 is Veterans Day! We take a look back at four veterans of the United States military who had a kratom story to share. From episode #13, Drew Turner is a US Navy veteran who served in Iraq and Guantanamo Bay. He appeared in the kratom documentary A Leaf of Faith. Drew discusses …

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63. Chewing Kratom Leaves with Soren Shade

Kratom Science Podcast
Kratom Science Podcast
63. Chewing Kratom Leaves with Soren Shade
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Soren Shade visits Brian in Pittsburgh bearing gifts: mature kratom leaves and a kratom plant the Top Tree Herbs greenhouse in West Virginia. This is the 2nd time the Hamilton’s Pharmacopeia producer and kratom entrepreneur has been on the podcast – the first time being #47. Brian chews kratom for the first time, and we …

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Journal Club #26: High Dose Mitragynine Causes Cognitive Impairment in Mice

Journal Club with Dr. Jonathan Cachat
Journal Club with Dr. Jonathan Cachat
Journal Club #26: High Dose Mitragynine Causes Cognitive Impairment in Mice
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Dr. JC and Brian look at a study out of University of Science, Malaysia. The comprehensive and detailed study in mice from University of Science, Malaysia revealed mitragynine in very high doses is an agonist (binds to and activates) cannabinoid receptor Type 1 (CB1). Mice administered with high-dose mitragynine demonstrated similar reward-seeking behavior and cognitive …

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62. Dr. Fabian Pitter Steinmetz, Toxicologist Who Testified at the WHO Hearing on Kratom

Kratom Science Podcast
Kratom Science Podcast
62. Dr. Fabian Pitter Steinmetz, Toxicologist Who Testified at the WHO Hearing on Kratom
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Dr. Fabian Pitter Steinmetz is a senior toxicologist from Germany and an outspoken advocate for harm reduction and science-based, rational drug policy. On October 11, 2021, representing the European Coalition for Just and Effective Drug Policies, Dr. Steinmetz testified against kratom prohibition for the World Health Organization’s 44th Expert Committee on Drug Dependence . Dr. …

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Journal Club #25: Dopamine Response to Mitragynine in Rats

Journal Club with Dr. Jonathan Cachat
Journal Club with Dr. Jonathan Cachat
Journal Club #25: Dopamine Response to Mitragynine in Rats
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Dr. Jon Cachat and host Brian Gallagher look at a study that examined dopamine levels with an electrochemical sensor in rats administered with various levels of mitragynine. Dopamine release was detected as significant levels after a high dose of mitragynine after 4 days. Questions explored in this episode include: Does this accurately measure the kratom …

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61. Ethan Nadelmann, Drug Policy Alliance Founder and Host of “PSYCHOACTIVE”

Kratom Science Podcast
Kratom Science Podcast
61. Ethan Nadelmann, Drug Policy Alliance Founder and Host of "PSYCHOACTIVE"
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PSYCHOACTIVE with Ethan Nadelmann https://cms.megaphone.fm/channel/psychoactive?selected=HSW1919502170My guest is one of the major critics of the War on Drugs and an advocate for science-based harm reduction policy. He is founder of the Drug Policy Alliance, an organization that’s been instrumental in marijuana legalization, and helped solicit comments for the 2016 fight to keep kratom legal, among other …

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60. Mr. Boston on Surviving 3 Near Death Experiences, Chronic Pain, and Multiple Sclerosis

Kratom Science Podcast
Kratom Science Podcast
60. Mr. Boston on Surviving 3 Near Death Experiences, Chronic Pain, and Multiple Sclerosis
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Mr. Boston, who chooses to remain anonymous, was pushed out of a tree at the age of 13 where he got a slipped disk and went on a regimen of gradually stronger and stronger opioids. Living with chronic pain, he later developed an even more painful autoimmune disorder, which he says feels like being attacked …

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59. Dr. Lance McMahon, Chair of University of Florida College of Pharmacy Dept of Pharmacodynamics

Kratom Science Podcast
Kratom Science Podcast
59. Dr. Lance McMahon, Chair of University of Florida College of Pharmacy Dept of Pharmacodynamics
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Dr. Lance McMahon is Chair of the Department of Pharmacodynamics at University of Florida College of Pharmacy, a college that has been at the forefront of kratom research. Dr. McMahon studies the mechanism of action of the multiple kratom alkaloids and how they function alone and in concert on our various brain receptors. His lab …

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