suboxone

Journal Club #33: Kratom Scientists Pen Letter Questioning Case Report Review

Journal Club with Dr. Jonathan Cachat
Journal Club with Dr. Jonathan Cachat
Journal Club #33: Kratom Scientists Pen Letter Questioning Case Report Review
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Dr. Cachat and Brian look at a letter (Smith et al, 2022) authored by former Kratom Science Podcast guests Dr. Kirsten Smith, Dr. Oliver Grundmann, Dr. Chris McCurdy, Dr. Darshan Singh, and other experts in the kratom field. The letter questions a systematic review (Broyan et al, 2022) of kratom case reports that offers buprenorphine …

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Journal Club #21: Heroin to Buprenorphine to Kratom in Appalachia

Journal Club with Dr. Jonathan Cachat
Journal Club with Dr. Jonathan Cachat
Journal Club #21: Heroin to Buprenorphine to Kratom in Appalachia
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Study examined in this episode: Smith, K. E., Bunting, A. M., Walker, R., Hall, M. T., Grundmann, O., & Castillo, O. (2019). Non-Prescribed Buprenorphine Use Mediates the Relationship between Heroin Use and Kratom Use among a Sample of Polysubstance Users. Journal of psychoactive drugs, 51(4), 311–322. https://doi.org/10.1080/02791072.2019.1597224Pubmed link https://pubmed.ncbi.nlm.nih.gov/30961450/ Link to all studies covered on …

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43. Kratom Addiction w. Dr Cornel Stanciu and Dr. Thomas Penders

Kratom Science Podcast
Kratom Science Podcast
43. Kratom Addiction w. Dr Cornel Stanciu and Dr. Thomas Penders
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My guests are two addiction psychiatrists, Dr. Cornel Stanciu and Dr. Thomas Penders. I responded to their webinar in episode 38. I thought they overstated the dangers of kratom and wondered why you’d prescribe buprenorphine for kratom withdrawals. We talk about that, and the topic of kratom addiction and addiction in general. Studies referenced to …

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Journal Club w/ Dr. Jonathan Cachat #5: Mitragynine Study in Rats Leads to Interesting Conclusions

Journal Club with Dr. Jonathan Cachat
Journal Club with Dr. Jonathan Cachat
Journal Club w/ Dr. Jonathan Cachat #5: Mitragynine Study in Rats Leads to Interesting Conclusions
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Dr. Cachat and I talk about a study that tested rats with morphine, mitragynine, naloxone, buprenorphine, and rimonabant, and measured responses based on food-reinforcement training. The study concluded “The findings suggest that MG does not induce physiological dependence but can alleviate the physical symptoms associated with morphine withdrawal”. We talk about how the rats are …

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Study: Pure mitragynine “does not induce physiological dependence” in rats, treated morphine withdrawal more efficiently than buprenorphine

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Article Citation with Link to Full Text Harun N, Johari IS, Mansor SM, Shoaib M. Assessing physiological dependence and withdrawal potential of mitragynine using schedule-controlled behaviour in rats. Psychopharmacology (Berl). 2020;237(3):855-867. doi:10.1007/s00213-019-05418-6 Summary by KratomScience Rats were studied in two separate experiments: Experiment 1: Observing withdrawal in rats given morphine vs. rats given mitragynine Three …

Study: Pure mitragynine “does not induce physiological dependence” in rats, treated morphine withdrawal more efficiently than buprenorphine Read More »

22. An Artist’s Outlet: Suzette Prutsok’s Kratom Story

Kratom Science Podcast
Kratom Science Podcast
22. An Artist's Outlet: Suzette Prutsok's Kratom Story
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My guest is Suzette Prutsok from Southern California. Suzette is an abstract artist and screenwriter. She was addicted to opiates for years, and after a couple attempts, got sober and made a profound change in her life with the help of kratom. This is Suzette Prutsok, and this is her kratom story. Suzette Prutsok’s art …

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