The conversation around kratom is as complex as the plant itself. For kratom to manifest in our society as a healing plant instead of a perceived dangerous drug, the science of kratom needs to become conventional wisdom. For the millions of Americans kratom has already helped, we can’t afford to spend 80 years digging our …
Why engaging with kratom misinformation hurts more than helps Read More »
A Vancouver drug company announced that it has filed a patent for a deuterated form of 7-hydroxymitragynine (7-HMG) called D7-h. The company, Nirvana Life Sciences Inc., intends to pursue D7-h as a pain relieving drug, citing 7-HMG’s partial opioid agonism, and the deuteration process that they say makes the drug last longer. A deuterated drug …
Is it a good idea to make a 7-hydroxymitragynine based drug? Read More »
Kailee joins Brian to look at the latest kratom news. This month we look at an investigative report asking questions about academic freedom at University of Florida that directly affected kratom scientists, past podcast guest Oliver Grundmann and Christopher McCurdy. Kratom regulations preventing sales to minors pass Pennsylvania House. A kratom consumer protection act is …
The audio version of this interview can be found as episode 30 of the Kratom Science Podcast. References to studies discussed are also listed there. Dr. Darshan Singh from the Center for Drug Research at the University of Science in Malaysia. Dr. Singh studies substance abuse, addiction treatment, and harm reduction. He has conducted multiple …
QR Code link https://enroll.drugabuse.gov/kratom-nida/ From the research team: About The KEMA Study We are conducting a new study on kratom entitled “Real-world momentary assessment of kratom use accompanied by product assays: A natural history study toward an interdisciplinary characterization of kratom use and pharmacology”! That is a long name, so we typically refer to it …
NIDA is rolling out a massive nationwide study of regular kratom consumers Read More »
Kailee joins Brian to discuss the latest in kratom legal, international, and science news for July 2022. Articles discussed in this episode: PA House passes bill banning sale of Kratom to minors https://www.wkbn.com/news/pennsylvania/pa-house-passes-bill-banning-sale-of-kratom-to-minors/ Online kratom sales okayed by [Thailand’s] House https://www.bangkokpost.com/thailand/general/2337463/online-kratom-sales-okayed-by-house Buddhist monks banned from using cannabis, except as medicine https://www.nationmultimedia.com/in-focus/40017260 “Kratom use as more …
Dr. Cachat and Brian look at a letter (Smith et al, 2022) authored by former Kratom Science Podcast guests Dr. Kirsten Smith, Dr. Oliver Grundmann, Dr. Chris McCurdy, Dr. Darshan Singh, and other experts in the kratom field. The letter questions a systematic review (Broyan et al, 2022) of kratom case reports that offers buprenorphine …
Journal Club #33: Kratom Scientists Pen Letter Questioning Case Report Review Read More »
Spoiler alert: kinda, but its more the quercetin in kratom, which is available in many food plants and as a dietary supplement on its own. This study comes to us from a team at Universitas Nahdlatul Ulama Surabaya (UNUSA) in Surabaya, Indonesia, on the island of Java, south of the island of Kalimantan, where most …
Journal Club #27: Does Kratom Kill…E-coli and Streptococcus Pneumoniae? Read More »
Dr. Lance McMahon is Chair of the Department of Pharmacodynamics at University of Florida College of Pharmacy. Dr. McMahon is involved in pioneering kratom research that looks at the various kratom alkaloids, how they function on our brain receptors, and how that creates kratom’s complex effects on our bio. We talk about this research, where …
Dr. JC and Brian look at a study out of University of Science, Malaysia. The comprehensive and detailed study in mice from University of Science, Malaysia revealed mitragynine in very high doses is an agonist (binds to and activates) cannabinoid receptor Type 1 (CB1). Mice administered with high-dose mitragynine demonstrated similar reward-seeking behavior and cognitive …
Journal Club #26: High Dose Mitragynine Causes Cognitive Impairment in Mice Read More »
