Cleveland Clinic is one of the highest ranking and most reputable hospital systems in the United States. The nonprofit established in 1921 (Happy Anniversary!) serves over 7 million patients per year, houses the top cardiology program in the nation, and has international campuses in Canada, the UK, and the United Arab Emirates. The Cleveland Clinic …
What is CBG? Many have heard about CBD, but are you familiar with CBG? Yeah, you read that right, CBG, or in long-form, Cannabigerolic acid (CBGA), is an all-essential aspect of any cannabis plant. A cannabinoid in it’s own right, CBGA serves as the mother to all other cannabinoids. Meaning, CBGA is the very first …
An audio version of this interview can be found on the Kratom Science Podcast #40 Kratom Science: How did you become involved with studying kratom? Oliver Grundmann: It’s an interesting way, how I got involved with kratom. In 2015 one of my Masters students who works in the forensic field with a forensic toxicology lab …
A new study from Thailand (La-up, 2021) found traditional users of kratom had elevated levels of high-density lipoprotein (HDL or “good” cholesterol) and low levels of triglycerides, or “fats from the food we eat that are carried in the blood” (Cleveland Clinic 2019). High HDL, low levels of low-density lipoprotein (LDL or “bad” cholesterol), and …
Correlation Found Between Thai Kratom Users and “Good” Cholesterol Levels Read More »
In a departure from kratom science, Dr. Cachat and Brian look at a paper by a pioneering pharmacologist and researcher in the field of psychedelics, Dr. David E. Nichols. Dr. Nichols methodically lays out his case for why endogenous DMT produced in the pineal gland, brain, or other parts of the human body is not …
Journal Club #18: Pineal Gland and DMT Facts and Myth Read More »
Take the new anonymous kratom survey! tinyurl.com/kratomteasurvey Hamilton Morris, creator of Hamilton’s Pharmacopeia, and producer Soren Shade talk to University of Florida scientist and past Kratom Science Podcast guest Dr. Oliver Grundmann about his new anonymous research survey on kratom tea. All kratom consumers are invited to participate. Plus, how an overly positive kratom narrative …
Hamilton Morris, Soren Shade, and Dr. Oliver Grundmann Talk Kratom and a New Survey Read More »
Most of the world’s commercial kratom is produced in Indonesia. A ban in Indonesia would be severely detrimental to the kratom supply. Kratom is illegal to sell as a food or medicine domestically in Indonesia, but as it grows wild there, those who use kratom can easily obtain it from native trees. It is legal …
Another study from University of Florida is the “first report that has simultaneously evaluated the systemic exposure of 11 kratom alkaloids following the administration of traditional and commercial kratom products” (Kamble, 2021). Researchers looked at the pharmacokinectics (how drugs move through the body and are metabolized) of alkaloids in rat plasma following the oral administration …
Journal Club #16: Bioanalysis of 11 Alkaloids in Kratom Tea vs. Commercial Extract Read More »
For audio of this interview as well as studies cited here see Kratom Science Podcast #45 KratomScience: You have your background in pharmacokinetics. What made you interested in going into that field? Dr. Abhisheak Sharma: So basically I did my PhD in 2015 and I moved to the States to do my post-doctoral studies with …
Inteview with Pharmacokineticist and Kratom Researcher Dr. Abhisheak Sharma Read More »
Dr. Abisheak Sharma studied pharmacy and pharmacokinetics in India before coming to the United States to research under kratom expert Dr. Bonnie Avery. He now researches kratom with Dr. Christopher McCurdy at University of Florida as part of the Translational Drug Development Core. Dr. Sharma addresses the concern with kratom and other drug interactions, improved …
45. Dr. Abisheak Sharma, Pharmacokineticist and Kratom Researcher Read More »
