Kratom as a Harm Reduction Tool

The term harm reduction refers to a public health strategy to reduce negative consequences resulting from activities such as illicit substance use and addiction. Whereas abstinence from dangerous drugs may…

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39. Recovery in the UK with Paul W.

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Paul W was prescribed hydrocodone following a car accident... the beginning of a long journey with opioid pain pills. Living in Florida during the golden age of pill mills (early…

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Is Kratom a Drug?
1950s ad for methedrine, aka legal methamphetamine

Is Kratom a Drug?

Is kratom a drug, a medicinal herb, a dietary supplement, a "safe food", a tea? These terms have a whole lot to do with social perception, a little to do…

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38. Psychiatrists Overstate the Dangers of Kratom

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In a recent webinar, psychiatrists describe kratom as dangerous with lethal overdose and toxicity potential. Using the studies they cite, Brian Gallagher explains why the dose of mitragyinine to establish…

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Toxic Levels of Kratom and LD50 of Mitragynine
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Toxic Levels of Kratom and LD50 of Mitragynine

Mitragynine is the most abundant alkaloid in kratom. Kratom contains about 40 alkaloids that we know of. All of the alkaloids combined make up only 0.5-1.5% of the total leaf…

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“Kratom addiction” used as defense in trial of Customs Officer who stole thousands from travelers

Joseph Cialone, a US Customers officer, is being charged with a felony for stealing approximately $10,000 from travelers coming into the United States in violation of 18 U.S. Code § 654.…

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5. Journal Club with Dr. Jonathan Cachat – Mitragynine Study in Rats Leads to Interesting Conclusions

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Dr. Cachat and I talk about a study that tested rats with morphine, mitragynine, naloxone, buprenorphine, and rimonabant, and measured responses based on food-reinforcement training. The study concluded "The findings…

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