6. Journal Club with Dr. Jonathan Cachat – 1972 Animal Study Shows the Promise of Mitragynine

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Citation: Macko E, Weisbach JA, Douglas B. Some observations on the pharmacology of mitragynine. Archives Internationales de Pharmacodynamie et de Therapie. 1972 ;198(1):145-161. We discuss this study from 1972 that…

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5. Journal Club with Dr. Jonathan Cachat – Mitragynine Study in Rats Leads to Interesting Conclusions

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Dr. Cachat and I talk about a study that tested rats with morphine, mitragynine, naloxone, buprenorphine, and rimonabant, and measured responses based on food-reinforcement training. The study concluded "The findings…

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Study: Pure mitragynine “does not induce physiological dependence” in rats, treated morphine withdrawal more efficiently than buprenorphine
photo by riccardo ragione, downloaded from usplash

Study: Pure mitragynine “does not induce physiological dependence” in rats, treated morphine withdrawal more efficiently than buprenorphine

Article Citation with Link to Full Text Harun N, Johari IS, Mansor SM, Shoaib M. Assessing physiological dependence and withdrawal potential of mitragynine using schedule-controlled behaviour in rats. Psychopharmacology (Berl).…

Continue Reading Study: Pure mitragynine “does not induce physiological dependence” in rats, treated morphine withdrawal more efficiently than buprenorphine