pain management

Journal Club #14, Q&A Part 1: Kratom and Liver Enzymes, Alcohol, Pain Management, and Serotonin

Kratom Science
Kratom Science
Journal Club #14, Q&A Part 1: Kratom and Liver Enzymes, Alcohol, Pain Management, and Serotonin
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Note: Nothing in this podcast or on KratomScience.com is intended to be medical advice, nor should it be taken as such. We’re not medical doctors. Please don’t listen to podcasts for advice on what you should or should not put in your body. For episode #14, Dr. Jonathan Cachat answers half of the remaining question …

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Journal Club #9: Speciofoline, the Understudied Alkaloid

Kratom Science
Kratom Science
Journal Club #9: Speciofoline, the Understudied Alkaloid
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A study on kratom’s chemical composition asks, what does the little-researched kratom alkaloid speciofoline do? And what are the implications for drug interactions and the differences in alkaloid content in kratom products? The brand new study published last week in Scientific Reports examined the chemical composition of 53 kratom products and divided them into two …

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Journal Club #8: Kratom Tea for Opioid Dependence in Mice

Kratom Science
Kratom Science
Journal Club #8: Kratom Tea for Opioid Dependence in Mice
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This week we look at a study by a team from University of Florida called “Lyophilized Kratom Tea as a Therapeutic Option for Opioid Dependence”. The science is catching up with what thousands of kratom consumers are saying — that kratom can be a safe and effective harm reduction tool for opioid withdrawal and dependence. …

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39. Recovery in the UK with Paul W.

Kratom Science
Kratom Science
39. Recovery in the UK with Paul W.
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Paul W was prescribed hydrocodone following a car accident… the beginning of a long journey with opioid pain pills. Living in Florida during the golden age of pill mills (early 2000s) didn’t help. After addiction, recovery, and relapse Paul moved to Italy where he met his future husband. They moved to England where Paul relapsed …

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Journal Club #6: 1972 Animal Study Shows the Promise of Mitragynine

Kratom Science
Kratom Science
Journal Club #6: 1972 Animal Study Shows the Promise of Mitragynine
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Citation: Macko E, Weisbach JA, Douglas B. Some observations on the pharmacology of mitragynine. Archives Internationales de Pharmacodynamie et de Therapie. 1972 ;198(1):145-161. We discuss this study from 1972 that tested the effects of mitragynine in rats, mice, cats, dogs, and monkeys. Dr. Jon talks about the difference between now and then in pharmacology labs. …

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Journal Club w/ Dr. Jonathan Cachat #5: Mitragynine Study in Rats Leads to Interesting Conclusions

Kratom Science
Kratom Science
Journal Club w/ Dr. Jonathan Cachat #5: Mitragynine Study in Rats Leads to Interesting Conclusions
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Dr. Cachat and I talk about a study that tested rats with morphine, mitragynine, naloxone, buprenorphine, and rimonabant, and measured responses based on food-reinforcement training. The study concluded “The findings suggest that MG does not induce physiological dependence but can alleviate the physical symptoms associated with morphine withdrawal”. We talk about how the rats are …

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33. Pain Management for Interstitial Cystitis with Maranda Flynn

Kratom Science
Kratom Science
33. Pain Management for Interstitial Cystitis with Maranda Flynn
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Maranda was diagnosed at 22 with interstitial cystitis, a painful bladder disease. She went into pain management and became addicted to opiates. After 3 years a friend introduced her to kratom. she got out of opiate hell, and was able to be present for her children and husband, who also used kratom to beat alcoholism. …

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Dr. Drew trashes chronic pain patients as “borderline druggies”

Last week on his podcast This Life You Live, celebrity addiction specialist Dr. Drew Pinsky called chronic pain patients “borderline druggies” for seeking medical treatment in the form of pain medication. Not surprisingly, this angered thousands of chronic pain patients who are now struggling to receive proper treatment from their doctors in the aftermath of …

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