opioids

46. Surviving Decades-Long Severe Chronic Pain with Dijon Evans

Kratom Science
46. Surviving Decades-Long Severe Chronic Pain with Dijon Evans
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Dijon Evans is a survivor of severe chronic pain, and as past Kratom Science Podcast guest Nina Ajdin refers to her, a warrior. At 16 and working as a lifeguard, Dijon injured her leg trying to save a little boy from drowning. Doctors applied a cast too tight, and despite days of pleading, they would …

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14. Journal Club Q&A Part 1: Kratom and Liver Enzymes, Alcohol, Pain Management, and Serotonin

Kratom Science
14. Journal Club Q&A Part 1: Kratom and Liver Enzymes, Alcohol, Pain Management, and Serotonin
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Note: Nothing in this podcast or on KratomScience.com is intended to be medical advice, nor should it be taken as such. We’re not medical doctors. Please don’t listen to podcasts for advice on what you should or should not put in your body. For episode #14, Dr. Jonathan Cachat answers half of the remaining question …

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45. Dr. Abisheak Sharma, Pharmacokineticist and Kratom Researcher

Kratom Science
45. Dr. Abisheak Sharma, Pharmacokineticist and Kratom Researcher
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Dr. Abisheak Sharma studied pharmacy and pharmacokinetics in India before coming to the United States to research under kratom expert Dr. Bonnie Avery. He now researches kratom with Dr. Christopher McCurdy at University of Florida as part of the Translational Drug Development Core. Dr. Sharma addresses the concern with kratom and other drug interactions, improved …

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13. Journal Club: How Kratom Alkaloids Act on Brain Receptors

Kratom Science
13. Journal Club: How Kratom Alkaloids Act on Brain Receptors
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We all know the mitragynine and 7-hydroxymitraginine act on the mu-opioid receptor. But for episode #13 of Journal Club we talk about a study that looks closely at the binding affinity of various kratom alkaloids on the plethora of opioid and adrenergic receptors in the brain. How exactly does this work? How do different alkaloids …

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44. Biomedical Educator and Research Scientist Dr. Walter Prozialeck

Kratom Science
44. Biomedical Educator and Research Scientist Dr. Walter Prozialeck
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My guest is Dr. Walter Prozialeck. Originally from Johnstown, PA, Dr. Prozialeck is a biomedical educator and researcher at Midwestern University in Chicago, where he served as chair of the Department of Pharmacology from 1997 to 2018. He’s been studying kratom since 2012. We talk about one of the first research reviews published on kratom …

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43. Kratom Addiction w. Dr Cornel Stanciu and Dr. Thomas Penders

Kratom Science
43. Kratom Addiction w. Dr Cornel Stanciu and Dr. Thomas Penders
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My guests are two addiction psychiatrists, Dr. Cornel Stanciu and Dr. Thomas Penders. I responded to their webinar in episode 38. I thought they overstated the dangers of kratom and wondered why you’d prescribe buprenorphine for kratom withdrawals. We talk about that, and the topic of kratom addiction and addiction in general. Studies referenced to …

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Plant Medicine: Cannabis, Kratom, and Psychedelics: An Interview with Dr. Zach Walsh

Audio version Kratom Science Podcast #42 KratomScience: Canada was one of the first countries to fully legalize cannabis. This was in 2018. Has there been an impact on the research that you can do in Canada because of legalization? Dr. Zach Walsh: Yes and no. The big moment for us with legalization and research really …

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Kratom and Alcoholism

Scientists have found evidence that kratom can help alleviate opioid withdrawal and cut down on cravings for recovering opiate addicts. Emerging research and experiential testimony indicates that kratom also cuts down on alcohol cravings and in some cases eliminates the desire to drink altogether. In a 2011 case study in European Psychiatry, researchers found “The …

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9. Journal Club: Speciofoline, the Understudied Alkaloid

Kratom Science
9. Journal Club: Speciofoline, the Understudied Alkaloid
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A study on kratom’s chemical composition asks, what does the little-researched kratom alkaloid speciofoline do? And what are the implications for drug interactions and the differences in alkaloid content in kratom products? The brand new study published last week in Scientific Reports examined the chemical composition of 53 kratom products and divided them into two …

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40. Dr. Oliver Grundmann

Kratom Science
40. Dr. Oliver Grundmann
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Dr. Oliver Grundmann is a Clinical Associate Professor with a PhD in Pharmaceutical Sciences and a masters’ in Forensic Toxicology, and expert in the study of kratom. University of Florida College of Pharmacy, where Dr. Grundmann works, has been a recipient of nearly $7 million in NIDA grants in 2018 and 2019 for the study …

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