metabolism

45. Dr. Abisheak Sharma, Pharmacokineticist and Kratom Researcher

Kratom Science
45. Dr. Abisheak Sharma, Pharmacokineticist and Kratom Researcher
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Dr. Abisheak Sharma studied pharmacy and pharmacokinetics in India before coming to the United States to research under kratom expert Dr. Bonnie Avery. He now researches kratom with Dr. Christopher McCurdy at University of Florida as part of the Translational Drug Development Core. Dr. Sharma addresses the concern with kratom and other drug interactions, improved …

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13. Journal Club: How Kratom Alkaloids Act on Brain Receptors

Kratom Science
13. Journal Club: How Kratom Alkaloids Act on Brain Receptors
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We all know the mitragynine and 7-hydroxymitraginine act on the mu-opioid receptor. But for episode #13 of Journal Club we talk about a study that looks closely at the binding affinity of various kratom alkaloids on the plethora of opioid and adrenergic receptors in the brain. How exactly does this work? How do different alkaloids …

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9. Journal Club: Speciofoline, the Understudied Alkaloid

Kratom Science
9. Journal Club: Speciofoline, the Understudied Alkaloid
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A study on kratom’s chemical composition asks, what does the little-researched kratom alkaloid speciofoline do? And what are the implications for drug interactions and the differences in alkaloid content in kratom products? The brand new study published last week in Scientific Reports examined the chemical composition of 53 kratom products and divided them into two …

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37. Sober October Starts Early

Kratom Science
37. Sober October Starts Early
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Just me this time around. I talk about a soon-to-be-released document I’ve been working on through COVID that’s 200 pages of kratom testimonials from over 800 consumers who posted to KratomScience.com. I talk about a study on kratom and metabolism I blogged about here https://www.kratomscience.com/2020/09/22/study-shows-mitragynine-metabolizes-into-7-hydroxomitragynine/. And I talk about my own history of drinking alcohol …

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2. Journal Club with Dr. Jonathan Cachat: “The Potential for Kratom as an Antidepressant and Antipsychotic”

Kratom Science
2. Journal Club with Dr. Jonathan Cachat: "The Potential for Kratom as an Antidepressant and Antipsychotic"
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This is the Kratom Science Journal Club with Dr. Jonathan Cachat, neuroscientist and expert in psychopharmacology. In each episode we discuss an article in a peer reviewed journal. For episode 2 we discuss the article, “The Potential for Kratom as an Antidepressant and Antipsychotic” published in Yale Journal of Biology and Medicine, edition 93, June …

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