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16. Journal Club: Bioanalysis of 11 Alkaloids in Kratom Tea vs. Commercial Extract

Kratom Science
16. Journal Club: Bioanalysis of 11 Alkaloids in Kratom Tea vs. Commercial Extract
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Another study from University of Florida is the “first report that has simultaneously evaluated the systemic exposure of 11 kratom alkaloids following the administration of traditional and commercial kratom products” (Kamble, 2021). Researchers looked at the pharmacokinectics (how drugs move through the body and are metabolized) of alkaloids in rat plasma following the oral administration …

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14. Journal Club Q&A Part 1: Kratom and Liver Enzymes, Alcohol, Pain Management, and Serotonin

Kratom Science
14. Journal Club Q&A Part 1: Kratom and Liver Enzymes, Alcohol, Pain Management, and Serotonin
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Note: Nothing in this podcast or on KratomScience.com is intended to be medical advice, nor should it be taken as such. We’re not medical doctors. Please don’t listen to podcasts for advice on what you should or should not put in your body. For episode #14, Dr. Jonathan Cachat answers half of the remaining question …

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13. Journal Club: How Kratom Alkaloids Act on Brain Receptors

Kratom Science
13. Journal Club: How Kratom Alkaloids Act on Brain Receptors
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We all know the mitragynine and 7-hydroxymitraginine act on the mu-opioid receptor. But for episode #13 of Journal Club we talk about a study that looks closely at the binding affinity of various kratom alkaloids on the plethora of opioid and adrenergic receptors in the brain. How exactly does this work? How do different alkaloids …

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43. Kratom Addiction w. Dr Cornel Stanciu and Dr. Thomas Penders

Kratom Science
43. Kratom Addiction w. Dr Cornel Stanciu and Dr. Thomas Penders
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My guests are two addiction psychiatrists, Dr. Cornel Stanciu and Dr. Thomas Penders. I responded to their webinar in episode 38. I thought they overstated the dangers of kratom and wondered why you’d prescribe buprenorphine for kratom withdrawals. We talk about that, and the topic of kratom addiction and addiction in general. Studies referenced to …

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Kratom and Alcoholism

Scientists have found evidence that kratom can help alleviate opioid withdrawal and cut down on cravings for recovering opiate addicts. Emerging research and experiential testimony indicates that kratom also cuts down on alcohol cravings and in some cases eliminates the desire to drink altogether. In a 2011 case study in European Psychiatry, researchers found “The …

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9. Journal Club: Speciofoline, the Understudied Alkaloid

Kratom Science
9. Journal Club: Speciofoline, the Understudied Alkaloid
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A study on kratom’s chemical composition asks, what does the little-researched kratom alkaloid speciofoline do? And what are the implications for drug interactions and the differences in alkaloid content in kratom products? The brand new study published last week in Scientific Reports examined the chemical composition of 53 kratom products and divided them into two …

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37. Sober October Starts Early

Kratom Science
37. Sober October Starts Early
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Just me this time around. I talk about a soon-to-be-released document I’ve been working on through COVID that’s 200 pages of kratom testimonials from over 800 consumers who posted to KratomScience.com. I talk about a study on kratom and metabolism I blogged about here https://www.kratomscience.com/2020/09/22/study-shows-mitragynine-metabolizes-into-7-hydroxomitragynine/. And I talk about my own history of drinking alcohol …

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Rare side effects could be from adulterated kratom, says scientist

Darshan Singh from the University of Science in Malaysia has been studying kratom for several years. A social scientist, Dr. Singh has found kratom to increase social functioning, lower withdrawal symptoms, and lower risk behaviors among opaite addicts in Malaysia. While Dr. Singh says kratom can cause an addiction similar to that of coffee, many …

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30. Dr. Darshan Singh

Kratom Science
30. Dr. Darshan Singh
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My guest is Dr. Darshan Singh from the Center for Drug Research at the University of Science in Malaysia. Dr. Singh studies substance abuse, addiction treatment, and harm reduction. He has conducted multiple studies of kratom consumers, and has found kratom in its pure form to be a safe and effective way to decrease substance …

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