A survey conducted from 2019-2020 found the majority of the 2,296 respondents with psychiatric conditions reported improvement in their condition following the consumption of kratom. On a scale of 1 to 10, 1 being “much worse” and 10 being “much better”, most people who use kratom (PWUK) who have been diagnosed with ADHD, PTSD, depression, …
People with psychiatric conditions report improvement after kratom use Read More »
Today on Journal Club, Dr. Jon Cachat look at a study in 2021 out of University of Colorado, Boulder in cooperation with Leafly that examines nearly 90,000 cannabis samples. Does Indica, Sativa, and Hybrid really mean anything in terms of psychoactive effects? Are cannabis strains labelled consistently in terms of cannabinoid and terpene content? We …
Journal Club #32: Cannabis Strains, Cannabinoids, and Terpenes Read More »
Dr. Cachat and host Brian Gallagher look at a groundbreaking study from University of Florida School of Pharmacy showing mitragynine has pain relieving effects independent of its metabolism into 7-hydroxymitragynine. This could be revolutionary in the study of kratom as a safer pain medicine. We go on to talk about the cannabis testing lab that …
In a new study by the team at University of Florida, scientists found that the metabolite 7-hydroxymitragynine does not account for the pain-relieving effects of its parent alkaloid, mitragynine (Berthold et al., 2021). Here we investigated the hotplate antinociception, pharmacokinetics, and tissue distribution of mitragynine and 7-hydroxymitragynine at equianalgesic oral doses in…mice to determine the …
Dr. Fabian Pitter Steinmetz is a senior toxicologist from Germany and an outspoken advocate for harm reduction and science-based, rational drug policy. On October 11, 2021, representing the European Coalition for Just and Effective Drug Policies, Dr. Steinmetz testified against kratom prohibition for the World Health Organization’s 44th Expert Committee on Drug Dependence . Dr. …
62. Dr. Fabian Pitter Steinmetz, Toxicologist Who Testified at the WHO Hearing on Kratom Read More »
A pharmacologist today may regard traditional and plant medicine as primitive, and may entirely disregard thousands of years of use and thousands of modern-day testimonies of positive outcomes because it has not been through the rigors of hard science. On the other hand, the massive spread of anti-science misinformation has cast sometimes unreasonable doubt on …
Combining traditional plant medicine with modern medical technology Read More »
Is kratom a drug, a medicinal herb, a dietary supplement, a “safe food”, a tea? These terms have a whole lot to do with social perception, a little to do with legal issues, and nothing to do with science. Kratom is a shrub that grows natively in Southeast Asia. Botanically, kratom comes from the Rubiaceae …
Article Citation with Link to Full Text Harun N, Johari IS, Mansor SM, Shoaib M. Assessing physiological dependence and withdrawal potential of mitragynine using schedule-controlled behaviour in rats. Psychopharmacology (Berl). 2020;237(3):855-867. doi:10.1007/s00213-019-05418-6 Summary by KratomScience Rats were studied in two separate experiments: Experiment 1: Observing withdrawal in rats given morphine vs. rats given mitragynine Three …
Jacob Ringstad never liked opiates. But at 18 he was diagnosed with Degenerative Disk Disease. At 19 he was injured in car accidents. This would lead to over a decade of managing chronic pain with opiates. Three years ago Jacob decided to get sober for the sake of his daughter. Using kratom and cannabis, Jacob …
31. A Kratom and Cannabis Success Story with Jacob Ringstad Read More »
Suzette is an abstract artist and screenwriter. She was addicted to opiates for years, and after a couple attempts, got sober and made a profound change in her life with the help of kratom. This is Suzette Prutsok, and this is her kratom story. Suzette Prutsok’s art can be seen on Instragram @lagtime_artTwitter @SuzetteLPrutsok And …
