withdrawal

8. Journal Club: Kratom Tea for Opioid Dependence in Mice

Kratom Science
8. Journal Club: Kratom Tea for Opioid Dependence in Mice
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This week we look at a study by a team from University of Florida called “Lyophilized Kratom Tea as a Therapeutic Option for Opioid Dependence”. The science is catching up with what thousands of kratom consumers are saying — that kratom can be a safe and effective harm reduction tool for opioid withdrawal and dependence. …

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7. Journal Club: Kratom Use and Mental Health w/ Dr. Marc Swogger and Dr. Jonathan Cachat

Kratom Science
7. Journal Club: Kratom Use and Mental Health w/ Dr. Marc Swogger and Dr. Jonathan Cachat
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Host Brian Gallagher and Dr. Jonathan Cachat welcome Dr. Marc Swogger, social scientist and clinical psychologist at the University of Rochester Medical Center to discuss his 2018 article published in Drug and Alcohol Dependence “Kratom Use and Mental Health: A Systematic Review”. Along with co-author Zach Walsh, Dr. Swogger looked at all the literature published …

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38. Psychiatrists Overstate the Dangers of Kratom

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38. Psychiatrists Overstate the Dangers of Kratom
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In a recent webinar, psychiatrists describe kratom as dangerous with lethal overdose and toxicity potential. Using the studies they cite, Brian Gallagher explains why the dose of mitragyinine to establish LD50 in mice is far beyond the levels consumed in leaf and even extracted kratom, and why one investigation into coroners’ reports disproved claims of …

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5. Journal Club with Dr. Jonathan Cachat – Mitragynine Study in Rats Leads to Interesting Conclusions

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5. Journal Club with Dr. Jonathan Cachat - Mitragynine Study in Rats Leads to Interesting Conclusions
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Dr. Cachat and I talk about a study that tested rats with morphine, mitragynine, naloxone, buprenorphine, and rimonabant, and measured responses based on food-reinforcement training. The study concluded “The findings suggest that MG does not induce physiological dependence but can alleviate the physical symptoms associated with morphine withdrawal”. We talk about how the rats are …

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Study: Pure mitragynine “does not induce physiological dependence” in rats, treated morphine withdrawal more efficiently than buprenorphine

Article Citation with Link to Full Text Harun N, Johari IS, Mansor SM, Shoaib M. Assessing physiological dependence and withdrawal potential of mitragynine using schedule-controlled behaviour in rats. Psychopharmacology (Berl). 2020;237(3):855-867. doi:10.1007/s00213-019-05418-6 Summary by KratomScience Rats were studied in two separate experiments: Experiment 1: Observing withdrawal in rats given morphine vs. rats given mitragynine Three …

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30. Dr. Darshan Singh

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30. Dr. Darshan Singh
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My guest is Dr. Darshan Singh from the Center for Drug Research at the University of Science in Malaysia. Dr. Singh studies substance abuse, addiction treatment, and harm reduction. He has conducted multiple studies of kratom consumers, and has found kratom in its pure form to be a safe and effective way to decrease substance …

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27. Rodeo Riding Leads to Chronic Pain to Addiction to Recovery w/ Stephanie Van Dyke

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27. Rodeo Riding Leads to Chronic Pain to Addiction to Recovery w/ Stephanie Van Dyke
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Stephanie Van Dyke was on her way to a professional career in rodeo horse riding, until she had an accident, which would give her chronic pain for the rest of her life. As a result, she got prescribed and hooked on opiate pain pills. Her opiate addiction took 10 years away from her life and …

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Interview with Marc Swogger, University of Rochester social scientist

An audio version of this interview can be found here. Dr. Marc Swogger is an associate professor at the University of Rochester Medical Center, Department of Psychiatry. Dr. Swogger is a social scientist and psychologist who studies substance use. He has co-authored multiple studies on the individual and public health effects of the use of …

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25. Misty Brown

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25. Misty Brown
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Misty Brown was diagnosed with Degenerative Disk Disease in 2008 which led to an 11 year addiction to opiate painkillers. After being fired from pain management and detoxing, Misty watched the Netflix documentary A Leaf of Faith which she says changed her life. She found that kratom helped her live with her chronic pain from …

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