Tonight at 11:59 PM, the Department of Health and Human Services (HHS) will close comments on the notice “Temporary Placement of 7-Hydroxymitragynine Above a Specified Threshold in Schedule I; Request for Information“. The notice asks for specific information and scientific evidence about the threshold of 7-OH that should be allowable in kratom products. However, many …
On June 1, the National Institutes of Health (NIH) announced that mitragynine, the most abundant alkaloid in kratom, has been cleared as an Investigational New Drug (IND). With IND status, scientists at University of Florida are now authorized to study the effects of pure mitragynine in human subjects. National Institute on Drug Abuse (NIDA) Director …
NIH Approves Clinical Trials as Mitragynine Gets “Investigational New Drug” Status Read More »
A case series published recently in the Journal of Addiction examined 14 American patients of Community Medical Services, a healthcare company specializing in the medically assisted treatment of Opioid Use Disorder (OUD). The patients were diagnosed with Kratom Use Disorder (KUD) (Sherrick, 2026). The very brief report does not get into specifics about kratom product …
Kratom Use Disorder Treatment with Methadone an Ongoing Practice Read More »
This week we look at very interesting study led by Fredric Schiffer based on this theory of Dual Brain Psychology (DBP). DBP “posits that one brain hemisphere tends to be relatively mature and healthy, while the other hemisphere may be more affected by past traumas and supports a personality that is more prone to immature …
Journal Club #30: Can Light Therapy Relieve Opioid Craving? Read More »
“NO JUDGEMENT, NO SHAMING, NO PREACHING, JUST LOVE! (800) 484-3731 If you are going to use by yourself, call us! You will be asked for your first name, location, and the number you are calling from. An operator will stay on the line with you while you use. If you stop responding after using, the …
Dr. Kirsten Smith is a post-doc fellow at National Institute on Drug Abuse. With a background in social work and working with communities with substance use disorder, Dr. Smith was instrumental in introducing kratom research to NIDA’s Intramural Research Program, where she works in the in the Real-world Assessment, Prediction, and Treatment Unit. Dr. Smith …
55. Dr. Kirsten Smith of National Institute on Drug Abuse (NIDA) Read More »
Study examined in this episode: Smith, K. E., Bunting, A. M., Walker, R., Hall, M. T., Grundmann, O., & Castillo, O. (2019). Non-Prescribed Buprenorphine Use Mediates the Relationship between Heroin Use and Kratom Use among a Sample of Polysubstance Users. Journal of psychoactive drugs, 51(4), 311–322. https://doi.org/10.1080/02791072.2019.1597224Pubmed link https://pubmed.ncbi.nlm.nih.gov/30961450/ Link to all studies covered on …
Journal Club #21: Heroin to Buprenorphine to Kratom in Appalachia Read More »
In a recent article published in International Journal of Drug Policy, leading kratom researchers called on the FDA, DEA, and legislators to keep kratom legal, as placing kratom on Schedule 1 would impede research and cause damaging public health consequences. Authors included Chris McCurdy, Andrew Kruegal, Jack Henningfield, and the late Bonnie Avery (who passed …
Leading Kratom Scientists Call on FDA, DEA to Keep Kratom Legal Read More »
