opioid receptors

13. Journal Club: How Kratom Alkaloids Act on Brain Receptors

Kratom Science
13. Journal Club: How Kratom Alkaloids Act on Brain Receptors
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We all know the mitragynine and 7-hydroxymitraginine act on the mu-opioid receptor. But for episode #13 of Journal Club we talk about a study that looks closely at the binding affinity of various kratom alkaloids on the plethora of opioid and adrenergic receptors in the brain. How exactly does this work? How do different alkaloids …

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10. Journal Club: Kratom and Alcohol

Kratom Science
10. Journal Club: Kratom and Alcohol
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Happy Thanksgiving! The holidays after a rough year are always a great time to drink like a fish. In this episode we explore kratom and alcohol. Emerging testimony and research indicates kratom may be an effective harm reduction tool to cut down on alcohol consumption, withdrawal, and cravings. We read testimony from KratomScience.com commenters, then …

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Kratom and Alcoholism

Scientists have found evidence that kratom can help alleviate opioid withdrawal and cut down on cravings for recovering opiate addicts. Emerging research and experiential testimony indicates that kratom also cuts down on alcohol cravings and in some cases eliminates the desire to drink altogether. In a 2011 case study in European Psychiatry, researchers found “The …

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9. Journal Club: Speciofoline, the Understudied Alkaloid

Kratom Science
9. Journal Club: Speciofoline, the Understudied Alkaloid
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A study on kratom’s chemical composition asks, what does the little-researched kratom alkaloid speciofoline do? And what are the implications for drug interactions and the differences in alkaloid content in kratom products? The brand new study published last week in Scientific Reports examined the chemical composition of 53 kratom products and divided them into two …

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2. Journal Club with Dr. Jonathan Cachat: “The Potential for Kratom as an Antidepressant and Antipsychotic”

Kratom Science
2. Journal Club with Dr. Jonathan Cachat: "The Potential for Kratom as an Antidepressant and Antipsychotic"
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This is the Kratom Science Journal Club with Dr. Jonathan Cachat, neuroscientist and expert in psychopharmacology. In each episode we discuss an article in a peer reviewed journal. For episode 2 we discuss the article, “The Potential for Kratom as an Antidepressant and Antipsychotic” published in Yale Journal of Biology and Medicine, edition 93, June …

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1. Kratom Science Journal Club with Dr. Jonathan Cachat

Kratom Science
1. Kratom Science Journal Club with Dr. Jonathan Cachat
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Dr. Jonathan Cachat joins Kratom Science Podcast host Brian Gallagher to talk about kratom research. Each episode we pick a study about kratom published in a peer-reviewed journal. This week we discuss “Patterns and Reasons for Kratom (Mitragyna speciosa) Use among Current and Former Opioid Poly-Drug Users” published in Journal of Ethnopharmacology, March 2020. Full …

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