My guest is Maxime Ruel from Quebec Canada. Max was a construction worker who was electrocuted on the job.. This led to extreme chronic pain that put him out of work. He eventually became homeless. After trying several medications he discovered kratom, which he says saved his life. This is Maxime Ruel, and this is …
The most studied alkaloids of the 40 identified in kratom are mitragynine (MG) and 7-hydroxymitragynine (7-OH). Recently, a team of researchers studied speciofoline (C22H28N2O5), a kratom alkaloid present in less than 1% of alkaloids. They found that speciofoline does not bind to mu-opioid receptors (MOR) like MG and 7-OH. They also found unexpectedly that levels …
What is speciofoline? The understudied kratom alkaloid Read More »
A study on kratom’s chemical composition asks, what does the little-researched kratom alkaloid speciofoline do? And what are the implications for drug interactions and the differences in alkaloid content in kratom products? The brand new study published last week in Scientific Reports examined the chemical composition of 53 kratom products and divided them into two …
Journal Club #9: Speciofoline, the Understudied Alkaloid Read More »
Dr. Oliver Grundmann is a Clinical Associate Professor with a PhD in Pharmaceutical Sciences and a masters’ in Forensic Toxicology, and expert in the study of kratom. University of Florida College of Pharmacy, where Dr. Grundmann works, has been a recipient of nearly $7 million in NIDA grants in 2018 and 2019 for the study …
This week we look at a study by a team from University of Florida called “Lyophilized Kratom Tea as a Therapeutic Option for Opioid Dependence”. The science is catching up with what thousands of kratom consumers are saying — that kratom can be a safe and effective harm reduction tool for opioid withdrawal and dependence. …
Journal Club #8: Kratom Tea for Opioid Dependence in Mice Read More »
The term harm reduction refers to a public health strategy to reduce negative consequences resulting from activities such as illicit substance use and addiction. Whereas abstinence from dangerous drugs may be ideal, it’s not always realistic to expect abstinence from every addict at every stage of their addiction. Whether it’s handing out clean hypodermic needles …
Do you have attention deficit hyperactivity disorder (ADHD) and consume kratom? Or have you tried kratom for ADHD symptoms or side effects of medications? How did it make you feel? Did kratom interact positively or negatively with other meds? We’d love to hear from you. Please leave a reply at the bottom of this page …
Host Brian Gallagher and Dr. Jonathan Cachat welcome Dr. Marc Swogger, social scientist and clinical psychologist at the University of Rochester Medical Center to discuss his 2018 article published in Drug and Alcohol Dependence “Kratom Use and Mental Health: A Systematic Review”. Along with co-author Zach Walsh, Dr. Swogger looked at all the literature published …
Is kratom a drug, a medicinal herb, a dietary supplement, a “safe food”, a tea? These terms have a whole lot to do with social perception, a little to do with legal issues, and nothing to do with science. Kratom is a shrub that grows natively in Southeast Asia. Botanically, kratom comes from the Rubiaceae …
In a recent webinar, psychiatrists describe kratom as dangerous with lethal overdose and toxicity potential. Using the studies they cite, Brian Gallagher explains why the dose of mitragyinine to establish LD50 in mice is far beyond the levels consumed in leaf and even extracted kratom, and why one investigation into coroners’ reports disproved claims of …
38. Psychiatrists Overstate the Dangers of Kratom Read More »
