pharmacology

Journal Club #9: Speciofoline, the Understudied Alkaloid

Journal Club with Dr. Jonathan Cachat
Journal Club with Dr. Jonathan Cachat
Journal Club #9: Speciofoline, the Understudied Alkaloid
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A study on kratom’s chemical composition asks, what does the little-researched kratom alkaloid speciofoline do? And what are the implications for drug interactions and the differences in alkaloid content in kratom products? The brand new study published last week in Scientific Reports examined the chemical composition of 53 kratom products and divided them into two …

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40. Dr. Oliver Grundmann

Kratom Science Podcast
Kratom Science Podcast
40. Dr. Oliver Grundmann
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Dr. Oliver Grundmann is a Clinical Associate Professor with a PhD in Pharmaceutical Sciences and a masters’ in Forensic Toxicology, and expert in the study of kratom. University of Florida College of Pharmacy, where Dr. Grundmann works, has been a recipient of nearly $7 million in NIDA grants in 2018 and 2019 for the study …

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Journal Club #6: 1972 Animal Study Shows the Promise of Mitragynine

Journal Club with Dr. Jonathan Cachat
Journal Club with Dr. Jonathan Cachat
Journal Club #6: 1972 Animal Study Shows the Promise of Mitragynine
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Citation: Macko E, Weisbach JA, Douglas B. Some observations on the pharmacology of mitragynine. Archives Internationales de Pharmacodynamie et de Therapie. 1972 ;198(1):145-161. We discuss this study from 1972 that tested the effects of mitragynine in rats, mice, cats, dogs, and monkeys. Dr. Jon talks about the difference between now and then in pharmacology labs. …

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