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Scientists: Kratom Extract “A Blessing and a Curse”

In a letter to the journal Addiction, kratom scientists including Oliver Grundmann, Christopher McCurdy, Abhisheak Sharma, Kirsten Smith, and Marc Swogger emphasized that kratom leaf, sold in crushed or dried for in the West and used for at least hundreds of years in Southeast Asia, is different from kratom alkaloid extract products, manufactured recently and …

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Media Conflates Milder Kratom Leaf with Stronger Kratom Extract

Recent media reports about kratom-related deaths are leaving out basic information about these tragic events. Preexisting conditions and possible drug interactions are sparsely mentioned or left out of reports entirely. Media is also using the term “kratom” to describe all products, from fresh leaf to extract to kratom products mixed with other substances (such as …

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Journal Club #16: Bioanalysis of 11 Alkaloids in Kratom Tea vs. Commercial Extract

Journal Club with Dr. Jonathan Cachat
Journal Club with Dr. Jonathan Cachat
Journal Club #16: Bioanalysis of 11 Alkaloids in Kratom Tea vs. Commercial Extract
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Another study from University of Florida is the “first report that has simultaneously evaluated the systemic exposure of 11 kratom alkaloids following the administration of traditional and commercial kratom products” (Kamble, 2021). Researchers looked at the pharmacokinectics (how drugs move through the body and are metabolized) of alkaloids in rat plasma following the oral administration …

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