speciofoline

What is speciofoline? The understudied kratom alkaloid

The most studied alkaloids of the 40 identified in kratom are mitragynine (MG) and 7-hydroxymitragynine (7-OH). Recently, a team of researchers studied speciofoline (C22H28N2O5), a kratom alkaloid present in less than 1% of alkaloids. They found that speciofoline does not bind to mu-opioid receptors (MOR) like MG and 7-OH. They also found unexpectedly that levels …

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Journal Club #9: Speciofoline, the Understudied Alkaloid

Journal Club with Dr. Jonathan Cachat
Journal Club with Dr. Jonathan Cachat
Journal Club #9: Speciofoline, the Understudied Alkaloid
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A study on kratom’s chemical composition asks, what does the little-researched kratom alkaloid speciofoline do? And what are the implications for drug interactions and the differences in alkaloid content in kratom products? The brand new study published last week in Scientific Reports examined the chemical composition of 53 kratom products and divided them into two …

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