mitragyna speciosa

Tennessee Lawmakers Push Kratom Ban Amid Controversy Over Misinformation

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NASHVILLE—A group of Republican lawmakers in the Tennessee House has signaled its intention to crack down on the controversial botanical substance known as kratom, sponsoring a resolution that suggests an outright ban or, at minimum, restrictive regulations. The measure, House Joint Resolution 147 (HJR147), has raised alarms among kratom advocates who argue that lawmakers are …

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What is speciofoline? The understudied kratom alkaloid

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The most studied alkaloids of the 40 identified in kratom are mitragynine (MG) and 7-hydroxymitragynine (7-OH). Recently, a team of researchers studied speciofoline (C22H28N2O5), a kratom alkaloid present in less than 1% of alkaloids. They found that speciofoline does not bind to mu-opioid receptors (MOR) like MG and 7-OH. They also found unexpectedly that levels …

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