drug research

Study: Mitragynine does not rely on its metabolism into 7-hydroxymitragynine to produce pain relieving effects

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In a new study by the team at University of Florida, scientists found that the metabolite 7-hydroxymitragynine does not account for the pain-relieving effects of its parent alkaloid, mitragynine (Berthold et al., 2021). Here we investigated the hotplate antinociception, pharmacokinetics, and tissue distribution of mitragynine and 7-hydroxymitragynine at equianalgesic oral doses in…mice to determine the …

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45. Dr. Abisheak Sharma, Pharmacokineticist and Kratom Researcher

Kratom Science Podcast
Kratom Science Podcast
45. Dr. Abisheak Sharma, Pharmacokineticist and Kratom Researcher
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Dr. Abisheak Sharma studied pharmacy and pharmacokinetics in India before coming to the United States to research under kratom expert Dr. Bonnie Avery. He now researches kratom with Dr. Christopher McCurdy at University of Florida as part of the Translational Drug Development Core. Dr. Sharma addresses the concern with kratom and other drug interactions, improved …

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Interview with Dirk Netter, author of the first German language book about kratom

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Dirk Netter is the author of the first major German language book on kratom. Kratom – Ethnobotanik, Anwendung, Kultur (English: Kratom – Ethnobotany, Application, and Culture) is soon to be released by Nachtschatten Verlag (Nightshade Press), a publisher from Switzerland. In 2018, Netter founded HIPF, or Hochschulgruppe für interdisziplinäre psychedelische Forschung, translated to English: the …

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Banning Drugs is Anti-Science, Anti-Health, and Anti-Social

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“Thankfully now, this is legal. The whole idea of Schedule 1, I think, is going to go away. How bizarre is that? That these molecules are ‘evil’. Please, come on!” That is a direct quote from celebrity addiction medicine specialist Dr. Drew Pinsky on his new YouTube podcast, “Dr. Drew After Dark”, recorded in California …

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