Mitragynine is the most abundant alkaloid in kratom. Kratom contains about 40 alkaloids that we know of. All of the alkaloids combined make up only 0.5-1.5% of the total leaf material. Estimates of percentage of mitragynine in alkaloids range from 12% in Malaysian kratom to 66% in Thai kratom. If alkaloids make up only 1% …
Joseph Cialone, a US Customers officer, is being charged with a felony for stealing approximately $10,000 from travelers coming into the United States in violation of 18 U.S. Code § 654. Over a period of a year, Cialone would target handbags and discreetly snatch money with a closed fist, then remove the latex glove from the …
Citation Kruegel AC, Uprety R, Grinnell SG, et al. 7-Hydroxymitragynine Is an Active Metabolite of Mitragynine and a Key Mediator of Its Analgesic Effects. ACS Cent Sci. 2019;5(6):992-1001. doi:10.1021/acscentsci.9b00141 Summary by KratomScience A study published in 2019 in the open access journal ACS Central Science found what may be a game changer in the pharmacology …
Study shows mitragynine metabolizes into 7-Hydroxymitragynine Read More »
Article Citation with Link to Full Text Harun N, Johari IS, Mansor SM, Shoaib M. Assessing physiological dependence and withdrawal potential of mitragynine using schedule-controlled behaviour in rats. Psychopharmacology (Berl). 2020;237(3):855-867. doi:10.1007/s00213-019-05418-6 Summary by KratomScience Rats were studied in two separate experiments: Experiment 1: Observing withdrawal in rats given morphine vs. rats given mitragynine Three …
Darshan Singh from the University of Science in Malaysia has been studying kratom for several years. A social scientist, Dr. Singh has found kratom to increase social functioning, lower withdrawal symptoms, and lower risk behaviors among opaite addicts in Malaysia. While Dr. Singh says kratom can cause an addiction similar to that of coffee, many …
Rare side effects could be from adulterated kratom, says scientist Read More »
The audio version of this interview can be found on Episode 24 of the Kratom Science Podcast. Kami Ann Davis was in a rafting accident in her 20s that led to a life of chronic pain.. She went on to become a nurse. The physical strain of nursing combined with the opioid medications for her …
An audio version of this interview can be found here. Dr. Marc Swogger is an associate professor at the University of Rochester Medical Center, Department of Psychiatry. Dr. Swogger is a social scientist and psychologist who studies substance use. He has co-authored multiple studies on the individual and public health effects of the use of …
Interview with Marc Swogger, University of Rochester social scientist Read More »
Suzette is an abstract artist and screenwriter. She was addicted to opiates for years, and after a couple attempts, got sober and made a profound change in her life with the help of kratom. This is Suzette Prutsok, and this is her kratom story. Suzette Prutsok’s art can be seen on Instragram @lagtime_artTwitter @SuzetteLPrutsok And …
by Brian Gallagher for KratomScience.com Listen to this story on Episode 20 of the Kratom Science Podcast. All her life Jennifer Van Blunk dreamed of being in the United States Navy until an injury prevented her from completing basic training. The physical and emotional pain led to a decade of opiate addiction. After years on …
Kratom Stories: Jennifer Van Blunk from Philadelphia Read More »
Chad G suffered through a 6-year opiate addiction that threatened his life and career. Twice, he nearly died of a heroin overdose..This dark period of Chad’s life came to an end when, he says, he discovered kratom and never looked back. Now he’s engaged to be married and runs his family’s business. KratomScience: When did …