6. Journal Club with Dr. Jonathan Cachat – 1972 Animal Study Shows the Promise of Mitragynine

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Citation: Macko E, Weisbach JA, Douglas B. Some observations on the pharmacology of mitragynine. Archives Internationales de Pharmacodynamie et de Therapie. 1972 ;198(1):145-161. We discuss this study from 1972 that…

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“Kratom addiction” used as defense in trial of Customs Officer who stole thousands from travelers

Joseph Cialone, a US Customers officer, is being charged with a felony for stealing approximately $10,000 from travelers coming into the United States in violation of 18 U.S. Code § 654.…

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37. Sober October Starts Early

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Just me this time around. I talk about a soon-to-be-released document I've been working on through COVID that's 200 pages of kratom testimonials from over 800 consumers who posted to…

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5. Journal Club with Dr. Jonathan Cachat – Mitragynine Study in Rats Leads to Interesting Conclusions

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Dr. Cachat and I talk about a study that tested rats with morphine, mitragynine, naloxone, buprenorphine, and rimonabant, and measured responses based on food-reinforcement training. The study concluded "The findings…

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Study: Pure mitragynine “does not induce physiological dependence” in rats, treated morphine withdrawal more efficiently than buprenorphine
photo by riccardo ragione, downloaded from usplash

Study: Pure mitragynine “does not induce physiological dependence” in rats, treated morphine withdrawal more efficiently than buprenorphine

Article Citation with Link to Full Text Harun N, Johari IS, Mansor SM, Shoaib M. Assessing physiological dependence and withdrawal potential of mitragynine using schedule-controlled behaviour in rats. Psychopharmacology (Berl).…

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4. Journal Club with Dr. Jonathan Cachat: Human Evolution and Psychoactive Plants, Scratching the Surface of Kratom History, and Kratom Alkaloids

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This episode, Dr. Jon and I use the journal article "Following the Roots of Kratom" published in 2015 by BioMed Research International as a jumping off point to talk about…

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2. Journal Club with Dr. Jonathan Cachat: “The Potential for Kratom as an Antidepressant and Antipsychotic”

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This is the Kratom Science Journal Club with Dr. Jonathan Cachat, neuroscientist and expert in psychopharmacology. In each episode we discuss an article in a peer reviewed journal. For episode…

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