Disclaimer: Preclinical studies on compounds’ effects on test animals do not always demonstrate exactly how compounds will affect humans A new study in rats examined the respiratory effects of mitragyinine (MG), considered the main compound in most kratom leaves consumed by users, and 7-hydroxymitragyinine (7-HMG) that occurs in very trace amounts in dried kratom leaf …
Read the full study, where the above image can be found: https://pmc.ncbi.nlm.nih.gov/articles/PMC12040156 Researchers at Kasetsart University and Chulalongkorn University in Bangkok, Thailand found that when insects like beetles, butterflies, and true bugs feed on kratom, the plant produces more mitragynine as a defense mechanism. This increase is also linked to higher leaf acidity. Plants produce …
Study Shows Kratom Leaves Attacked by Insects Have Higher Mitragynine Read More »
The United States House Committee on Appropriations has allocated the Agency for Healthcare Research and Quality (AHRQ) $500,000 towards kratom research for the year of 2021. The AHRQ was given a budget of $338,000,000 in total. “The Committee is aware of the potential promise of kratom-derived compounds for acute and chronic pain patients who seek safer …
Say what you will about kratom, but you will be hard pressed to find information or personal testimonies doubting that it has serious potential as a harm reduction tool. With overdose deaths rising at historic rates, this is a tool that we need now more than ever. It saddens me to write an article such …
December 2020 The Agency for Healthcare and Research Quality (AHRQ) is currently conducting a systematic review on plant-based treatment for chronic pain. Their goal: “identify alternative treatments (to opioids) with equal or better benefits for pain while avoiding potential unintended consequences.” Specifically, they will be reviewing the benefits and potential harms of cannabinoids and kratom. …
In a recent article published in International Journal of Drug Policy, leading kratom researchers called on the FDA, DEA, and legislators to keep kratom legal, as placing kratom on Schedule 1 would impede research and cause damaging public health consequences. Authors included Chris McCurdy, Andrew Kruegal, Jack Henningfield, and the late Bonnie Avery (who passed …
Leading Kratom Scientists Call on FDA, DEA to Keep Kratom Legal Read More »
Slowly but surely, government is responding to the relentless advocacy of the kratom community and the American Kratom Association. In addition to the state governments of Georgia, Utah, and Arizona (that recently decided to regulate rather than ban kratom), the House of Representatives and the National Institutes on Drug Abuse are listening to our calls …