Research – Page 6 – Kratom Science

Plant Medicine: Cannabis, Kratom, and Psychedelics: An Interview with Dr. Zach Walsh

Leave a Comment / General, Research / By Brian

Audio version Kratom Science Podcast #42 KratomScience: Canada was one of the first countries to fully legalize cannabis. This was in 2018. Has there been an impact on the research that you can do in Canada because of legalization? Dr. Zach Walsh: Yes and no. The big moment for us with legalization and research really …

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Kratom: Providing Hope Amidst a Pan/Epi-demic

1 Comment / Current Events, Research / By Andrew

Say what you will about kratom, but you will be hard pressed to find information or personal testimonies doubting that it has serious potential as a harm reduction tool. With overdose deaths rising at historic rates, this is a tool that we need now more than ever. It saddens me to write an article such …

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Why the AHRQ Review On Chronic Pain Matters

1 Comment / Current Events, General, News, Research / By Andrew

December 2020 The Agency for Healthcare and Research Quality (AHRQ) is currently conducting a systematic review on plant-based treatment for chronic pain. Their goal: “identify alternative treatments (to opioids) with equal or better benefits for pain while avoiding potential unintended consequences.” Specifically, they will be reviewing the benefits and potential harms of cannabinoids and kratom. …

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Kratom and Alcoholism

2 Comments / General, Research / By Brian

Scientists have found evidence that kratom can help alleviate opioid withdrawal and cut down on cravings for recovering opiate addicts. Emerging research and experiential testimony indicates that kratom also cuts down on alcohol cravings and in some cases eliminates the desire to drink altogether. In a 2011 case study in European Psychiatry, researchers found “The …

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What is speciofoline? The understudied kratom alkaloid

Leave a Comment / General, Research / By Brian

The most studied alkaloids of the 40 identified in kratom are mitragynine (MG) and 7-hydroxymitragynine (7-OH). Recently, a team of researchers studied speciofoline (C22H28N2O5), a kratom alkaloid present in less than 1% of alkaloids. They found that speciofoline does not bind to mu-opioid receptors (MOR) like MG and 7-OH. They also found unexpectedly that levels …

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Kratom as a Harm Reduction Tool

2 Comments / General, Research / By Brian

The term harm reduction refers to a public health strategy to reduce negative consequences resulting from activities such as illicit substance use and addiction. Whereas abstinence from dangerous drugs may be ideal, it’s not always realistic to expect abstinence from every addict at every stage of their addiction. Whether it’s handing out clean hypodermic needles …

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Do you take kratom for ADHD ?

14 Comments / General, Research / By Brian

Do you have attention deficit hyperactivity disorder (ADHD) and consume kratom? Or have you tried kratom for ADHD symptoms or side effects of medications? How did it make you feel? Did kratom interact positively or negatively with other meds? We’d love to hear from you. Please leave a reply at the bottom of this page …

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Is Kratom a Drug?

5 Comments / General, Research / By Brian

Is kratom a drug, a medicinal herb, a dietary supplement, a “safe food”, a tea? These terms have a whole lot to do with social perception, a little to do with legal issues, and nothing to do with science. Kratom is a shrub that grows natively in Southeast Asia. Botanically, kratom comes from the Rubiaceae …

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Toxic Levels of Kratom and LD50 of Mitragynine

4 Comments / Research / By Brian

Mitragynine is the most abundant alkaloid in kratom. Kratom contains about 40 alkaloids that we know of. All of the alkaloids combined make up only 0.5-1.5% of the total leaf material. Estimates of percentage of mitragynine in alkaloids range from 12% in Malaysian kratom to 66% in Thai kratom. If alkaloids make up only 1% …

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