A new study published in Frontiers in Plant Science is presenting a clearer picture of how post-harvest processing changes the plant’s chemistry. The researchers from University of Florida and Oregon State University compared kratom varieties grown in Hawaii and Malaysia to see how factors like withering time, drying temperature, and harvest season influence alkaloid profiles—particularly …
Important to note: This does NOT mean severe health risks from kratom alone do not exist. There is a toxic amount of any substance that can be ingested, including kratom. The majority, but not all, of toxic adverse events associated with kratom have involved other substances, as well as substance misuse in general. Kratom should …
Review Finds Insufficient Evidence of Severe Health Risks From Kratom Alone Read More »
The kratom industry is railing against 7-OH products as problematic, but are extra-strength kratom extracts problematic too? The controversy surrounding the rise of new 7-hydroxymitragynine (7-OH) products has sparked a debate among various players in the kratom industry, as well as scientists and consumers. A debate called “The 7-OH Fault Line” took place at the …
Members of the American Kratom Association (AKA) and the Holistic Alternative Recovery Trust (HART) will debate the controversial alkaloid 7-hydroxymitragynine (7-OH) and the 7-OH-abundant products that have become available to consumers in the past 2 years. Billed as “The 7-OH Fault Line”, the debate will take place at the Las Vegas Convention Center 3150 Paradise …
AKA and HART Face Off Over 7-Hydroxymitragynine This Friday Read More »
Disclaimer: Kratom Is Not a Breast Cancer Treatment: While this study investigates the potential of kratom compounds mitragynine and 7-hyroxymitragynine to bind with HER2 receptors through computer modeling, it does not prove or suggest that kratom cures breast cancer. These results are preliminary and based solely on in silico simulations (i.e., computer-generated predictions). No clinical …
Preliminary in silico Study Explores Kratom Alkaloids’ Effects on Breast Cancer Protein Read More »
Thailand has announced funding for 33 new research and development projects for kratom. The National Herbal Medicines Policy Committee has listed the traditional plant as a “herb of the year” for 2025. Along with phlai and black ginger, special consideration will be given to promote kratom for export and for use in wellness centers and …
Thailand Launches 33 New Research and Development Projects for Kratom Read More »
Disclaimer: Preclinical studies on compounds’ effects on test animals do not always demonstrate exactly how compounds will affect humans A new study in rats examined the respiratory effects of mitragyinine (MG), considered the main compound in most kratom leaves consumed by users, and 7-hydroxymitragyinine (7-HMG) that occurs in very trace amounts in dried kratom leaf …
Health Claims in Texas Smoke Shops With a dearth of regulation and market enforcement, marketers of kratom, kratom-derived synthetics, and products like hemp and THC continue to employ shady business practices to sell their products. Researchers from university pharmacy and medicine departments conducted a secret shopper investigation at 100 smoke shops in San Antonio and …
Nefarious Marketing: Making Health Claims and Synthetics Sold as “Kratom” Read More »
Read the full study, where the above image can be found: https://pmc.ncbi.nlm.nih.gov/articles/PMC12040156 Researchers at Kasetsart University and Chulalongkorn University in Bangkok, Thailand found that when insects like beetles, butterflies, and true bugs feed on kratom, the plant produces more mitragynine as a defense mechanism. This increase is also linked to higher leaf acidity. Plants produce …
Study Shows Kratom Leaves Attacked by Insects Have Higher Mitragynine Read More »
The Johns Hopkins University School of Medicine is conducting a groundbreaking online study on 7-hydroxymitragynine (7-OH), a compound associated with certain kratom products. The study invites individuals who have consumed 7-OH products to participate by completing a screening process and, if eligible, an online survey about their usage patterns. As a thank-you, participants who complete …
Johns Hopkins Seeks Participants for Online Study on 7-OH Kratom Products Read More »