Mitraphylline is an oxindole alkaloid, made mostly of carbon, hydrogen, nitrogen, and oxygen. It’s found in kratom at trace amounts (less than 1% of the total alkaloid makeup of kratom leaf). Cat’s Claw contains much more of the alkaloid: 1 gram of dried cat’s claw bark might contain 0.5 to 3 milligrams of mitraphylline. Research …
Scientists Discover How Plants Make Mitraphylline Read More »
Note: There is a correlation between kratom and seizures, but causation has not been established. Kratom alone or kratom combined with other substances could very well cause seizures in some consumers, but as this study shows, there is not enough evidence to determine causation. Seizures have been commonly listed as a side effect of kratom …
Scientists find “insufficient evidence to suggest that kratom causes seizures” Read More »
A new study published in Frontiers in Plant Science is presenting a clearer picture of how post-harvest processing changes the plant’s chemistry. The researchers from University of Florida and Oregon State University compared kratom varieties grown in Hawaii and Malaysia to see how factors like withering time, drying temperature, and harvest season influence alkaloid profiles—particularly …
Important to note: This does NOT mean severe health risks from kratom alone do not exist. There is a toxic amount of any substance that can be ingested, including kratom. The majority, but not all, of toxic adverse events associated with kratom have involved other substances, as well as substance misuse in general. Kratom should …
Review Finds Insufficient Evidence of Severe Health Risks From Kratom Alone Read More »
The kratom industry is railing against 7-OH products as problematic, but are extra-strength kratom extracts problematic too? The controversy surrounding the rise of new 7-hydroxymitragynine (7-OH) products has sparked a debate among various players in the kratom industry, as well as scientists and consumers. A debate called “The 7-OH Fault Line” took place at the …
Members of the American Kratom Association (AKA) and the Holistic Alternative Recovery Trust (HART) will debate the controversial alkaloid 7-hydroxymitragynine (7-OH) and the 7-OH-abundant products that have become available to consumers in the past 2 years. Billed as “The 7-OH Fault Line”, the debate will take place at the Las Vegas Convention Center 3150 Paradise …
AKA and HART Face Off Over 7-Hydroxymitragynine This Friday Read More »
In a statement released May 29, the Department of the Army Criminal Investigation Division (CID) warned soldiers about the “dangers of kratom”. Echoing language posted on the DEA or FDA website, the Army CID pointed out that kratom and its alkaloids are not FDA approved, and listed all possible side effects, but did not characterize …