kratom safety concerns

FDA Announces Plans to Schedule 7-OH as a Controlled Substance a Week After Kratom Industry Allegedly Staged 7-OH Protests

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On Tuesday, July 29, officials including Department of Health and Human Services (HHS) Secretary Robert F. Kennedy, Jr. and Food and Drug Administration (FDA) Commissioner Marty Makary announced via a press conference the FDA’s intent to recommend to the Drug Enforcement Administration (DEA) that 7-hydroxymitragynine (7-OH) be scheduled as a controlled substance. Several times during …

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Preliminary in silico Study Explores Kratom Alkaloids’ Effects on Breast Cancer Protein

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Disclaimer: Kratom Is Not a Breast Cancer Treatment: While this study investigates the potential of kratom compounds mitragynine and 7-hyroxymitragynine to bind with HER2 receptors through computer modeling, it does not prove or suggest that kratom cures breast cancer. These results are preliminary and based solely on in silico simulations (i.e., computer-generated predictions). No clinical …

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Study: Mitragynine Stimulated and 7-Hydroxymitragynine Depressed Respiratory Activity in Rats

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Disclaimer: Preclinical studies on compounds’ effects on test animals do not always demonstrate exactly how compounds will affect humans A new study in rats examined the respiratory effects of mitragyinine (MG), considered the main compound in most kratom leaves consumed by users, and 7-hydroxymitragyinine (7-HMG) that occurs in very trace amounts in dried kratom leaf …

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