kratom pharmacology

FDA Study on Kratom Published

A long-awaited kratom clinical study conducted by the U.S. Food and Drug Administration (FDA) has been published in the Journal of Clinical Psychopharmacology. The pilot study (defined as “a preliminary investigation designed to test the feasibility and design of a larger, more comprehensive study”) involved healthy adult participants who were administered an ascending dose of …

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Is 7-OH Really “13 times stronger than morphine”?

Multiple news media and even medical professionals have repeated the claim that 7-hydroxymitragynine (7-OH) is “13 times stronger than morphine” as though it is a fact established through rigorous science. Where does this claim come from and how accurate is it? The claim comes from studies from 2002 (Takayama, et al) and 2004 (Matsumoto, et …

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Scientists find “insufficient evidence to suggest that kratom causes seizures”

Note: There is a correlation between kratom and seizures, but causation has not been established. Kratom alone or kratom combined with other substances could very well cause seizures in some consumers, but as this study shows, there is not enough evidence to determine causation. Seizures have been commonly listed as a side effect of kratom …

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