Governor Andy Beshear of Kentucky announced that he is taking action to place 7-hydroxymitragynine on the list of Schedule I substances in Kentucky. The move will classify 7-OH in the same category as heroin, criminalizing 7-OH consumers in the bluegrass state. If it is determined that a substance poses an imminent threat to public safety, …
Mitraphylline is an oxindole alkaloid, made mostly of carbon, hydrogen, nitrogen, and oxygen. It’s found in kratom at trace amounts (less than 1% of the total alkaloid makeup of kratom leaf). Cat’s Claw contains much more of the alkaloid: 1 gram of dried cat’s claw bark might contain 0.5 to 3 milligrams of mitraphylline. Research …
Scientists Discover How Plants Make Mitraphylline Read More »
Scientists from British Columbia Institute of Technology and University of Illinois published a study that examines five 7-hydroxymitragynine (the abbreviation 7-OH has become popularized, but the scientists use 7-HMG in this study) products marketed as “kratom extracts”. A kratom extract is a concentrated form of the kratom plant made by extracting its active alkaloids, of …
Scientists Test 7-OH Products Marketed as ‘Kratom Extracts’ Read More »
A new study published in Frontiers in Plant Science is presenting a clearer picture of how post-harvest processing changes the plant’s chemistry. The researchers from University of Florida and Oregon State University compared kratom varieties grown in Hawaii and Malaysia to see how factors like withering time, drying temperature, and harvest season influence alkaloid profiles—particularly …
Important to note: This does NOT mean severe health risks from kratom alone do not exist. There is a toxic amount of any substance that can be ingested, including kratom. The majority, but not all, of toxic adverse events associated with kratom have involved other substances, as well as substance misuse in general. Kratom should …
Review Finds Insufficient Evidence of Severe Health Risks From Kratom Alone Read More »
The alkaloid 7-hydroxymitragynine (7-OH) is unique in that it occurs mostly as a metabolite of mitragynine (MG), the most abundant alkaloid in kratom. On July 29, the Food and Drug Administration (FDA) announced its intention to recommend scheduling of 7-OH on the list of federally controlled substances, but explicitly stated that its not going after …
Could Kratom Consumers Catch DUI if 7-OH is Banned? Read More »
The kratom industry is railing against 7-OH products as problematic, but are extra-strength kratom extracts problematic too? The controversy surrounding the rise of new 7-hydroxymitragynine (7-OH) products has sparked a debate among various players in the kratom industry, as well as scientists and consumers. A debate called “The 7-OH Fault Line” took place at the …
Members of the American Kratom Association (AKA) and the Holistic Alternative Recovery Trust (HART) will debate the controversial alkaloid 7-hydroxymitragynine (7-OH) and the 7-OH-abundant products that have become available to consumers in the past 2 years. Billed as “The 7-OH Fault Line”, the debate will take place at the Las Vegas Convention Center 3150 Paradise …
AKA and HART Face Off Over 7-Hydroxymitragynine This Friday Read More »
Read the full study, where the above image can be found: https://pmc.ncbi.nlm.nih.gov/articles/PMC12040156 Researchers at Kasetsart University and Chulalongkorn University in Bangkok, Thailand found that when insects like beetles, butterflies, and true bugs feed on kratom, the plant produces more mitragynine as a defense mechanism. This increase is also linked to higher leaf acidity. Plants produce …
Study Shows Kratom Leaves Attacked by Insects Have Higher Mitragynine Read More »