7-hydroxymitragynine

FDA Seizes Tens of Thousands of 7-OH Products from Missouri Warehouses

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The U.S. Marshals Service operating under an order from the Food and Drug Administration (FDA) seized approximately 73,000 7-hydroxymitragynine (7-OH) products from three Missouri warehouses. The warehouses are operated by Shaman Botanicals LLC (selling products under the American Shaman brand) and Relax Relief Rejuvenate Trading LLC (selling products under the Relax Relief Rejuvenate brand). American …

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Kratom Consumer Protection Bill Considered in Michigan; Sponsor Warns of Nonexistent “8-OH”

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A Kratom Consumer Protection Act (KCPA) bill that would regulate the distribution, sale, and manufacture of kratom products is being considered in the Michigan House. House Bill 4969 would: Given the 2% limit, this Kratom Consumer Protection Act and others effectively outlaw the sale of novel 7-hydroxymitragynine (7-OH) products that have been widely available since …

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Ohio Introduces Kratom Regulation Bill After Governor Called for Ban in August

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Senator Louis Blessing introduced a bill in the Ohio Senate that will regulate rather than ban kratom. Introduced on October 21, SB299 would limit the amount of naturally-occurring 7-hydroxymitragynine (7-OH) to less than 2% of alkaloids or 1 milligram per serving. All synthetic or semi-synthetic alkaloids will be made illegal to sell. Each product must …

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Scientists find “insufficient evidence to suggest that kratom causes seizures”

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Note: There is a correlation between kratom and seizures, but causation has not been established. Kratom alone or kratom combined with other substances could very well cause seizures in some consumers, but as this study shows, there is not enough evidence to determine causation. Seizures have been commonly listed as a side effect of kratom …

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Scientists Test 7-OH Products Marketed as ‘Kratom Extracts’

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Scientists from British Columbia Institute of Technology and University of Illinois published a study that examines five 7-hydroxymitragynine (the abbreviation 7-OH has become popularized, but the scientists use 7-HMG in this study) products marketed as “kratom extracts”. A kratom extract is a concentrated form of the kratom plant made by extracting its active alkaloids, of …

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California Dept of Public Health Seizes Kratom Despite Lack of Prohibition Laws

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Last week, the California Department of Public Health (CDPH) announced it has seized $5 million worth of kratom and 7-hydroxymitragynine (7-OH) products, despite no law explicitly prohibiting kratom and 7-OH in the state. Grant Boyken of CDPH told SFGATE the products were placed under embargo “pending further regulatory actions”. Boyken cited California’s Sherman Food, Drug, …

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Study: Kratom alkaloid make-up dependent on genetics, environmental factors, and processing

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A new study published in Frontiers in Plant Science is presenting a clearer picture of how post-harvest processing changes the plant’s chemistry. The researchers from University of Florida and Oregon State University compared kratom varieties grown in Hawaii and Malaysia to see how factors like withering time, drying temperature, and harvest season influence alkaloid profiles—particularly …

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Could Kratom Consumers Catch DUI if 7-OH is Banned?

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The alkaloid 7-hydroxymitragynine (7-OH) is unique in that it occurs mostly as a metabolite of mitragynine (MG), the most abundant alkaloid in kratom. On July 29, the Food and Drug Administration (FDA) announced its intention to recommend scheduling of 7-OH on the list of federally controlled substances, but explicitly stated that its not going after …

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Wave of Negative News Engulfs Kratom Since FDA Move to Schedule 7-OH

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A wave of negative media coverage (more than usual) has engulfed kratom in the weeks following the FDA’s July 29 recommendation to classify 7-hydroxymitragynine (7-OH) as an illicit substance. While the agency’s move targets products containing an abundance of 7-OH—not the plain leaf kratom that contains near-zero amounts of 7-OH—news outlets have blurred the distinction, …

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