Like kratom, I think that it is fair to say that us kratom consumers have been partially misunderstood and incorrectly labeled. In a world full of disinformation, it is easy to get lost in the madness. One day, you may see on the news a wild claim stating, “Man driven to psychosis by kratom.” Other …
Note: This article is a summary of the journal article cited as follows:Gonçalves, J., Luís, Â., Gallardo, E., & Duarte, A. P. (2021). Psychoactive Substances of Natural Origin: Toxicological Aspects, Therapeutic Properties and Analysis in Biological Samples. Molecules (Basel, Switzerland), 26(5), 1397. https://doi.org/10.3390/molecules26051397Full text: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961374/ Scientists from Portugal, where the possession and consumption of all …
List of “New” Psychoactive Substances of Natural Origin Read More »
Most of the world’s commercial kratom is produced in Indonesia. A ban in Indonesia would be severely detrimental to the kratom supply. Kratom is illegal to sell as a food or medicine domestically in Indonesia, but as it grows wild there, those who use kratom can easily obtain it from native trees. It is legal …
In a 2020 case report, a teenage girl intentionally overdosed on 45 kratom capsules (500mg each = 22.5 grams or 4/5 ounce). After suffering from severe depression, the 15 year old obtained the capsules from her father, and swallowed them in an attempted suicide. On exam, patient complained of dry mouth, dizziness, restlessness, palpitations, nausea, …
Teenager Attempts Suicide by Swallowing 45 Kratom Capsules Read More »
For audio of this interview as well as studies cited here see Kratom Science Podcast #45 KratomScience: You have your background in pharmacokinetics. What made you interested in going into that field? Dr. Abhisheak Sharma: So basically I did my PhD in 2015 and I moved to the States to do my post-doctoral studies with …
Inteview with Pharmacokineticist and Kratom Researcher Dr. Abhisheak Sharma Read More »
A team from the Department of Plant Biology at Michigan State University published the kratom genome, or the complete contents of genetic material in an organism. Using Rifat kratom trees grown in a greenhouse at the university, the team analyzed plant material to generate a draft assembly of mitragyna specioca for the first time. As …
A study out of University of Florida published in the journal ACS Pharmacology & Translational Science found that the potency of powder kratom may be due not only to the increased level of 7-hydroxymitragynine (7-HMG), but the way the 7-HMG metabolizes in human plasma (Kamble 2020). Fresh kratom consumed traditionally in Southeast Asia has been …
A research article in the journal Drug Testing and Analysis uncovered a flaw in previous examinations of kratom’s main alkaloid, mitragynine. The study, lead by University of Florida pharmacutics researcher Dr. Abisheak Sharma, stated: There is a possibility that earlier reported studies did not separate the four mitragynine diastereomers, resulting in over‐quantification of mitragynine in …
Levels of Kratom Alkaloid Mitragynine Were Likely Overestimated in Autopsies Read More »
Listen to this interview on Kratom Science Podcast #44 KratomScience: How do you pronounce your last name? Dr. Walter Prozialeck: Proh-jell-eck. It’s an old Ukrainian word that means “really bad golfer”. KS: *laughs* But I see you are a really good rugby player, it says on your Wikipedia page. WP: Well I used to be. …
Interview with Dr. Walter Prozialeck, Biomedical Educator and Kratom Researcher Read More »
DEPARTMENT OF HEALTH AND HUMAN SERVICESOffice of the SecretaryOffice of the Assistant Secretary for HealthWashington, D.C. 20201 AUG 16 2018 [stamped] The Honorable Uttam DhillonActing AdministratorDrug Enforcement AdministrationU.S. Department of Justice8701 Morrissette DriveSpringfield, VA 22152 Dear Mr. Dhillon: Pursuant to the Controlled Substances Act (CSA), 21 U.S.C. § 811, I am rescinding our prior recommendation …
Full Text of 2018 HHS Letter to DEA Rescinding Kratom Ban Recommendation Read More »