Can You Overdose On Kratom? In Short, No.

Can You Overdose On Kratom? In Short, No.

There seems to be a lot of misconception about people overdosing on kratom. Basically, it’s essentially impossible to actually overdose on the powdered leaf. The leaves contain a variety of alkaloids, 2 of which are primarily responsible for the plant’s opiate like effects, mitragynine and 7-hydroxymitragynine.

But the plant also contains what are believed to be opiate antagonists that become dominant over mitragynine and 7-hydroxymitragynine as dosage increases. This results in nausea, vomiting  and general unpleasantness. It’s almost impossible to consume more than 1 ounce of powdered leaf at a time before these negative side effects makes it undesirable to consume more.

At the one ounce level, the amount of mitragynine and 7-hydroxymitragynine present is not anywhere near enough to cause an overdose even for someone with absolutely no tolerance. In a sense, it’s a built in safety mechanism.

Some, but not all, extracts remove the opiate antagonists, allowing for more to be consumed without the negative side effects becoming overwhelming. But with these, as dosage increases the effects level off, such that past a certain point there are diminishing returns where consuming more doesn’t really have any effect. Furthermore, to consume enough to actually get near an overdose level, it would be cost prohibitive.

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This Post Has 115 Comments

  1. Matthias

    Let me inform the misinformed on this site who are throwing shade on Kratom. Coming from an opiate addict of 10 years, kratom is a lifesaver. All reports of deaths where kratom was present involved the intake of other more powerful illicit or licit drugs. Even if there were no other drugs present within the persons system does not attribute kratom as the sole reason for their death. It’s well known that kratom is used to ease withdraw symptoms from other drugs. Withdraws from heavy use of Benzos and sometimes opiates can kill you. This is no mystery and could be an explanation as to why there were no other drugs present in the system in the very very few deaths where kratom was the only thing present in the system. Except the government and FDA don’t want to tell you that. They are trying to scare the general public with misinformation. Think long and hard at why the FDA would want to spread misinformation about a natural herbal supplement to advance their agenda on making it illegal. It’s real simple!!! They have their hands in big pharma’s pockets. People who were using opioid painkillers are switching to kratom. This is no bueno for big pharma and their pockets which pay the FDA. They are lobbyists!! It’s for the same reason the FDA made L-tryptophan illegal back in the 90s because it was hurting big pharma and their sells on benzodiazepines. L-tryptophan is naturally occurring in Turkey!! What the hell?!! Watch the Netflix mini series called “The Pharmacist”. You’ll see that the FDA approved Purdue pharma and their OxyContin and ads sending a message that Opiate Pain killers were not addictive and a risk for abuse. It’s all about money and like I said any natural occurring plant that can be used as a supplement to deter people from taking exponentially more dangerous man made chemicals doled out by big pharma becomes a threat to their bottom line and pockets which in turn is a threat to the US governments pockets. Educate yourselves!!

  2. Harley

    red da magnea is the best in my opinion I love it!

  3. Annie

    Hello, I’ve been using red bali and red maeng da kratom powder for a few months now and it saved my life. I am 40 suffering from moderate degenerative disk disease and also digestive issues. I weigh 180 lbs. so a 3 gram dosage is perfect and I have no pain and have much better digestion! I hope it helps someone else!

  4. Gregory

    Robert I hope it did help you I’m also 50 years old and I have been on kratom for about a year it has helped my pain in my back I have chronic back pain I have found using different strains helps some of the stranes does not you just have to play around with them, I was taking oxycodone and Vicodin and tell my job said I can’t take them that’s so now I take kratom in order to keep working, remember God’s always there for us and he has put things down on this Earth to help us I believe this is one of them.

  5. Marc D

    Too much water will kill you. Look up how many people die a year from drinking too much water, skydiving, asprin or aleve (keep your liver and kidneys safe they say). Balance and being responsible folks. That’s all it takes. And no, not everyone will balance but to completely come down on something that helps more people than it hurts? Like medication including most Pharma pushed products, there will be risks that are outweighed by the benefits. We are all still learning as it’s newer here, but promising for those of us that need pain relief, anxiety relief or to help break free from the good ol products that we consume from big pharma. Funny… I can still go buy a pack of cigarettes or vodka. I can drink myself to death one night if i so choose. What I don’t have to buy are opiates, painkillers or other drugs at the local drugstore.

  6. Kaylee

    This is wrong. It is 100% possible to overdose and it to kill you. Talk to those touched by the shock of a death of a loved one. All toxicology screening and reports state it was an accidental over self medication with kratom. It’s not safe dont use it.

    1. Tyler

      There are no reported overdoses on kratom, they were all results of underlying health problems and mixing it with drugs.

    2. Larry

      Please let us know the exact science involved in the blood toxicology report that says kratom was the specific cause of death. So far I’ve found nothing factual just a lot of folks like you with claims. Even the govt. Has said that their findings are inconclusive. And let’s say folks are being stupid and overdosing how is this any different than the tens of thousands of deaths contributes to alcohol? This product obvs helps more people than it hurts.

  7. Bman

    Hey what strain are you using? I’m sick of taking pain meds(broke my neck TWICE 2mo apart a few years ago) because they just don’t work anymore and I’m trying the white and its, meh at best. Thanks!

  8. David

    Wtf it’s not heroin. It’s not laced, you definitely will not overdose. Just like you won’t die from thc

  9. Deb

    Hello I’m asking for my husband with out him knowing !! He has been abusing pain pills for years , last year he went to rehab and got on Suboxone ! He was on that for just about a year until his doctor kicked him out of the program he had a bad pee test ! Well someone told him about Kratom at 1st I was on board with it because he didn’t seem to be withdrawing and seem some better ! Well now I notice he is abusing the Kratom , he gets a 58 dollar bag of the red and makes his own he puts it into gel caps , that bag only last him a couple days ! This last past weekend he had a big bottle of Kratom called white Borneo it had 300 pills he took them all In about 3 days !! Please can someone tell me anything!

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